Research Keyword: Mycology diagnostics

Prevalence of Candida and Other Yeasts in Vulvovaginal Infections during Pregnancy: A 10-Year Serbian Survey

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This study examined yeast infections in pregnant Serbian women over 10 years, finding that nearly half had positive tests. While Candida albicans was most common, many other yeast species were also identified, some of which are resistant to common antifungal medications. Using advanced laboratory techniques (MALDI-TOF MS), researchers found more accurate identification was possible, which is important since different yeasts require different treatments, especially during pregnancy when some medications can harm the baby.

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Diagnostic Performance of a PCR-Based Approach for the Diagnosis of Dermatomycosis

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This study evaluated a new testing method combining DNA analysis (PCR) with traditional microscopy and culture to diagnose fungal skin, hair, and nail infections. The PCR method detects the infection quickly and accurately, identifying the specific fungus causing the problem within days rather than weeks. The study of over 4,400 samples found that Trichophyton rubrum was the most common cause of fungal infections, and the combined testing approach was 98.5% accurate while reducing unnecessary lab work.

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Performance of the VITEK® MS system for the identification of filamentous fungi in a microbiological laboratory in Chile

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This study tested a new laboratory technology called VITEK® MS for quickly identifying mold infections in patients. Researchers tested the system on 67 mold samples representing 35 different species. The technology successfully identified over 91% of the mold samples accurately without any misidentifications, making it a reliable tool for hospitals to quickly determine what type of mold is causing an infection so doctors can prescribe the right antifungal medication.

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Antifungal stewardship in the UK: where are we now?

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This paper examines how well the UK is currently managing antifungal stewardship—the appropriate use of antifungal medications to treat serious fungal infections while preventing resistance. Experts found that since 2017, progress has been limited due to lack of funding and staff expertise, difficulties accessing timely fungal diagnostic tests, and disruptions from the COVID-19 pandemic. The panel recommends creating regional mycology networks and diagnostic centres, establishing national standards for antifungal practices, and improving education about fungal infections to better prepare the UK for rising fungal disease threats.

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