Research Keyword: mycological culture

First occurrence of feline sporotrichosis in a metropolitan area of Central-West Brazil

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Researchers in Brazil discovered the first case of a serious fungal infection called sporotrichosis in a domestic cat in the Goiania metropolitan area. The infection was caused by a fungus called Sporothrix brasiliensis, which can spread from cats to humans through scratches and bites. This finding is important because it shows the disease is spreading to new regions of Brazil that previously didn’t have confirmed cases, and suggests residents need to be cautious around stray cats.

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Identification of fungal agents isolated from burn lesions using mycological and molecular methods in patients admitted to Velayat burn hospital in Rasht city during 2022–2023

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Researchers studied fungal infections in burn patients at a hospital in Iran and found that non-albicans Candida fungi, particularly a species called Candida parapsilosis, were the most common culprits. Using laboratory cultures and genetic testing, they identified 101 fungal infections out of 380 burn patients. Understanding which fungi cause these infections is important for doctors to choose the right treatment and improve patient outcomes.

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Evaluation of Clinical, Microbiological Profiles and Management Patterns with Outcomes of Patients with Fungal Isolates in An Intensive Care Unit of A Tertiary Care Center: A Prospective Observational Study

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This study examined fungal infections in intensive care unit patients at a major hospital in India. Researchers found that diabetes was the most common risk factor, and most infections were caused by Candida species found in urine samples. Many fungal isolates were resistant to common antifungal drugs like fluconazole, suggesting doctors need to be more careful about which medications they use to treat these infections.

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Systematic Review of Tinea Nigra: A Clinical Approach

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Tinea nigra is a rare fungal skin infection that causes dark spots, usually on the palms, and is most common in tropical regions. It primarily affects younger people and women. The infection is easily diagnosed using microscopic examination and treated successfully with topical antifungal creams like ketoconazole or Whitfield’s ointment, typically clearing within 4 weeks.

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Editorial: Dermatopathology and Associated Laboratory Investigations in the Study of Skin Disease

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This special journal issue brings together several studies on how doctors diagnose skin diseases using laboratory tests. The papers cover different methods including examining fungal infections under a microscope, using new staining techniques, and applying molecular tests to identify skin cancers and autoimmune conditions. Together, these studies show how combining pathology examination with laboratory techniques is essential for accurately diagnosing and treating various skin disorders.

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Extensive erythematous plaques of fungal origin in an overseas student: Cutaneous manifestation of coccidioidomycosis

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A 21-year-old student studying in Arizona developed unusual skin rashes months after returning to China. Doctors had difficulty diagnosing the condition because it lacked typical symptoms of the fungal infection coccidioidomycosis. By using multiple diagnostic methods including DNA sequencing and fungal culture, they identified the infection as caused by Coccidioides posadasii. When the initial antifungal drug didn’t work, testing showed the fungus was resistant, so they switched to a different antifungal called voriconazole, which successfully cured the infection after 12 months.

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Monoclonal Antibodies Can Aid in the Culture-Based Detection and Differentiation of Mucorales Fungi—The Flesh-Eating Pathogens Apophysomyces and Saksenaea as an Exemplar

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Researchers developed a new diagnostic tool using specially designed antibodies to quickly identify dangerous flesh-eating fungi (Apophysomyces and Saksenaea) that cause severe infections. These fungi are particularly difficult to diagnose because they don’t produce spores on standard laboratory cultures. The new test can identify these pathogens in just 24-48 hours, much faster than traditional methods, which is critical since these infections progress rapidly and require immediate treatment. This advancement is especially important for hospitals in developing countries where expensive diagnostic equipment is unavailable.

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