multilocus sequence typing

Clinical Isolate of Candida tropicalis from a Patient in North Carolina: Identification, Whole-Genome Sequence Analysis, and Anticandidal Activity of Ganoderma lucidum

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Researchers in North Carolina identified a drug-resistant yeast infection (Candida tropicalis) from a hospital patient and tested whether extracts from reishi mushrooms (Ganoderma lucidum) could kill it. Using genetic analysis, they found mutations in the yeast that help it resist antifungal drugs. All three types of mushroom extracts tested successfully stopped the yeast’s growth and damaged its cells, suggesting that reishi mushrooms could be a promising natural treatment option for hard-to-treat candida infections.

Sporothrix is neglected among the neglected

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Sporotrichosis is a fungal infection caused by Sporothrix species that usually affects the skin but can spread to joints, lungs, and eyes. While traditionally spread through plant material during gardening, the disease has increasingly spread between cats and humans through bites and scratches, particularly in South America and other regions. The fungus is developing resistance to common antifungal drugs, and scientists worry climate change could expand where this disease occurs worldwide.

Optimizing a modified cetyltrimethylammonium bromide protocol for fungal DNA extraction: Insights from multilocus gene amplification

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This research improves how scientists extract DNA from fungi found in dried fruits and other sources. The modified CTAB method is faster, cheaper, and produces higher quality DNA than commercial kits, without requiring special equipment like liquid nitrogen. The extracted DNA works well for identifying fungal species and detecting fungal diseases in fish, plants, and humans, making it valuable for both research and medical diagnostics.

Multilocus sequence typing of Candida albicans isolates from wild and farm animals from southern Italy

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Researchers in Italy studied a fungus called Candida albicans that can infect both humans and animals. They analyzed samples from chickens, wild boars, and lizards to understand how genetically similar these animal strains are to human infections. They found that animal strains are very similar to human strains, suggesting the fungus could be passed between animals and people. This research highlights the importance of monitoring fungal infections in animals to understand public health risks.

Isolation and molecular identification of pathogens causing sea turtle egg fusariosis in key nesting beaches in Costa Rica

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Researchers in Costa Rica discovered that a dangerous fungal disease affecting sea turtle eggs is more widespread than previously known. The disease, called sea turtle egg fusariosis, is caused by two types of fungi that can kill developing turtle embryos. Scientists used advanced genetic testing to identify these fungi at major turtle nesting beaches on both coasts of Costa Rica, finding one fungus present at all locations while another was found only on the Caribbean coast. While the disease is not severely harming Costa Rican sea turtles yet, environmental changes could make it worse in the future.

Isolation and molecular identification of pathogens causing sea turtle egg fusariosis in key nesting beaches in Costa Rica

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Scientists discovered that two harmful fungi, Fusarium falciforme and Fusarium keratoplasticum, are present on sea turtle nesting beaches across Costa Rica. These fungi can infect turtle eggs and cause high mortality rates in developing embryos. The researchers used advanced genetic techniques to accurately identify these pathogens and found them widespread at important nesting sites, highlighting the need for monitoring and protection strategies to prevent this emerging disease from becoming a major threat to sea turtle populations.

Multilocus sequence typing of Candida albicans isolates from wild and farm animals from southern Italy

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Researchers studied a fungal pathogen called Candida albicans found in farm and wild animals in Italy to understand how it spreads between animals and humans. They used genetic analysis to compare isolates from laying hens, wild boars, and lizards with samples from infected humans around the world. The results showed that animal isolates were genetically similar to human clinical samples, suggesting animals could serve as reservoirs for this infection. This research highlights the importance of monitoring fungal diseases in animal populations as part of understanding disease transmission between animals and people.

Optimizing a modified cetyltrimethylammonium bromide protocol for fungal DNA extraction: Insights from multilocus gene amplification

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Researchers developed an improved method for extracting fungal DNA that is faster, cheaper, and safer than current commercial kits. The new protocol works by using a special chemical solution and simple crushing tools instead of expensive equipment like liquid nitrogen or bead beaters. They tested it on 40 different fungal species found in dry fruits and successfully identified them all using genetic markers, showing the method could help diagnose fungal diseases in plants, animals, and humans.

Co-Infection of Pulmonary Aspergillosis and Cryptococcal Meningitis in an HIV-Positive Patient: A Case Report

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This case describes a man with undiagnosed HIV who developed two serious fungal infections at the same time: a lung infection caused by Aspergillus fungus and a brain infection caused by Cryptococcus fungus. His extremely low immune system (CD4 count of 41) made him vulnerable to multiple opportunistic infections. Despite treatment with antifungal medications, his condition worsened and he passed away, highlighting the dangers of late HIV diagnosis.

Identification and Pathogenicity of Fusarium Fungi Associated with Dry Rot of Potato Tubers

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Researchers identified different Fusarium fungi causing potato dry rot in Russia and tested how they grow at various temperatures and how aggressively they damage potatoes. They found that F. sambucinum is the most dangerous because it can grow and cause rot even during cold storage, unlike other species. This research helps farmers understand which pathogens threaten their crops and how storage conditions affect disease development.

Research Keyword: multilocus sequence typing