Research Keyword: mucus plug

Allergic Bronchopulmonary Mycosis Caused by Schizophyllum commune Successfully Treated With Mepolizumab

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A 70-year-old man developed a serious lung condition caused by a fungal infection (Schizophyllum commune) that resulted in dangerous mucus buildup and asthma attacks despite standard treatments. When traditional medications failed, doctors tried a newer biologic drug called mepolizumab that targets immune cells causing inflammation. The treatment successfully cleared the mucus, improved breathing, and allowed the patient to stop taking steroid medications while remaining symptom-free for over two years.

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Aspergillus Bronchitis at Localised Mucus Plug in an Immunocompetent Patient

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A 55-year-old woman developed a rare fungal infection called Aspergillus bronchitis in a mucus plug within her lung over a 9-year period. Although she was otherwise healthy with a normal immune system, the fungus gradually grew and eventually caused serious bleeding in her lungs. Doctors treated the bleeding with artery embolization and then surgically removed the affected lung tissue. The fungus was identified as Aspergillus udagawae, a type that is harder to treat with standard antifungal medications.

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