Research Keyword: mortality

The Hidden Microbial World in the Gut of the Terrestrial Snail Cornu aspersum maxima and the Unexpected Negative Effects of Synbiotics

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This study tested whether adding beneficial bacteria (probiotics) and dietary fibers (prebiotics) to snail farm feed could improve snail health and growth. While individual probiotic and prebiotic treatments helped reduce harmful bacteria in snails’ digestive systems, combining them together as a synbiotic surprisingly caused extremely high death rates in the snails. The results show that more research is needed before combining these supplements in snail farming.

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Trichosporon species bloodstream infections in a tertiary care hospital in the western region of Saudi Arabia: A 7-year retrospective chart review from 2016 to 2022

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This study examined a rare but dangerous fungal infection called Trichosporonosis that affects the bloodstream in hospitalized patients. Researchers found that this infection kills about 60% of patients despite treatment with antifungal medications. The infection is often caused by a fungus called Trichosporon asahii and typically occurs in patients with weakened immune systems who are already hospitalized and using catheters.

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Invasive fungal infections caused by rare yeast-like fungi in adult patients: results of a prospective study

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This study examined rare fungal infections in 30 critically ill adult patients over 18 years, finding that infections caused by uncommon yeasts like Trichosporon and Rhodotorula affected mainly long-term ICU patients with central lines. Despite treatment with antifungal medications, about 37% of patients died, highlighting the serious nature of these infections. The research emphasizes the importance of quickly identifying the specific fungus causing infection and using appropriate medications, along with removing infected catheters, to improve patient survival.

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Persistent Candidemia: Predictors and Outcomes in a Multicenter Matched Analysis

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This study examined cases where fungal infections caused by Candida persisted in the bloodstream even after starting antifungal treatment. Researchers compared 46 patients with persistent infections to 92 control patients without persistent infections across three major medical centers. Patients with persistent candidemia were younger, more likely to be female, had more health complications, and sadly had much higher death rates (54% vs 31%) within 90 days. The findings suggest that certain patient characteristics and fungal species types may help identify those at higher risk of persistent infections.

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Clinical insights into mixed Candida and bacterial bloodstream infections: a retrospective cohort study

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This study found that when both Candida fungus and bacteria are present together in a patient’s bloodstream, the outcome is much more serious than when only Candida is present. Among patients with these mixed infections, over 60% died within 30 days compared to about 52% for those with only Candida. The research shows that giving the right antibiotics early and following proper treatment guidelines can significantly improve survival chances in these severe, life-threatening infections.

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