Research Keyword: monosaccharide composition

Polysaccharides from Spores of Cordyceps cicadae Protect against Cyclophosphamide-Induced Immunosuppression and Oxidative Stress in Mice

Researchers extracted and studied special compounds called polysaccharides from the spores of Cordyceps cicadae, a medicinal fungus used in traditional Chinese medicine. When tested in mice treated with a cancer drug that suppresses immunity, one of these purified compounds (CCSP-2) successfully restored immune function and reduced harmful oxidative stress. The compound works by boosting the activity of immune cells and protecting the body’s natural antioxidant defense systems, suggesting it could potentially help cancer patients manage chemotherapy side effects.

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Recent advances in natural polysaccharides for type 2 diabetes management: sources, structural characteristics, and mechanistic insights

Natural polysaccharides from plants, mushrooms, and seaweed show promise as treatments for type 2 diabetes. These complex sugar molecules work through multiple mechanisms including improving how the body uses insulin, reducing inflammation and oxidative stress, and promoting beneficial gut bacteria. The effectiveness of these polysaccharides depends on their specific chemical structure, particularly their molecular weight and how their sugar units are linked together.

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Extraction Optimization and Bioactivity of Polysaccharides from Ganoderma leucocontextum Spores

Researchers developed an improved method to extract beneficial polysaccharides from Ganoderma leucocontextum (white Ganoderma), a rare mushroom from the Tibetan plateau. The extracted compound GLSP-A1 showed strong anti-inflammatory effects by reducing inflammatory markers and reduced signs of aging in test organisms by decreasing harmful reactive oxygen species and cellular aging pigments. This work suggests the mushroom polysaccharide could potentially be used in dietary supplements to help slow aging.

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Response mechanism of extracellular polymers in the remediation of chromium pollution by carbonate mineralizing bacteria

Certain bacteria can help clean up chromium pollution by producing protective coatings made of sugar and protein molecules. When exposed to high levels of chromium, these bacteria produce more of these protective coatings, which trap and neutralize the toxic metal. The coating changes its composition to better bind chromium, and the protein structure becomes more porous to catch more metal. This research shows how nature can be used to clean up contaminated environments.

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Screening and identifying natural products with SARS-CoV-2 infection inhibitory activity from medicinal fungi

Researchers screened 167 extracts from 36 medicinal fungi to find natural compounds that could fight COVID-19. They discovered that certain fungi, particularly Inonotus obliquus and Pholiota adiposa, contain polysaccharides that effectively block the virus from infecting cells. These natural compounds showed promise as potential safe alternatives for developing new COVID-19 treatments and may have applications against other viral diseases.

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Polysaccharides from fungi: A review on their extraction, purification, structural features, and biological activities

Mushrooms contain special compounds called polysaccharides that have powerful health benefits. Scientists have found these polysaccharides can help fight cancer, boost immunity, reduce inflammation, and manage diabetes. This review explains different ways to extract and purify these beneficial compounds from mushrooms and describes how they work in the body to provide these health benefits.

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Neutral Polysaccharides From Hohenbuehelia serotina With Hypoglycemic Effects in a Type 2 Diabetic Mouse Model

Researchers extracted and studied special compounds called polysaccharides from H. serotina mushrooms. They found that these compounds significantly reduced blood sugar levels in mice with type 2 diabetes and also protected the liver. The study shows that mushroom polysaccharides could be a safe, natural alternative to existing diabetes medications with fewer side effects.

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Isolation, purification, and structural elucidation of Stropharia rugosoannulata polysaccharides with hypolipidemic effect

Scientists extracted and studied a polysaccharide from wine cap mushrooms that shows promise for lowering cholesterol and protecting the liver. The compound, called SRF-3, has a complex sugar structure and works by binding to cholesterol and bile acids, helping the body eliminate them. Testing in laboratory conditions showed it has strong antioxidant properties and can reduce fat accumulation in liver cells, suggesting potential use as a natural supplement for managing high cholesterol.

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Structure and Bioactivity of Intracellular and Extracellular Polysaccharides of Trametes lactinea Mycelium

Researchers extracted and studied polysaccharides from Trametes lactinea mushroom mycelium grown in liquid culture. They found that these polysaccharides have strong antioxidant properties and can boost immune cell function, with the intracellular polysaccharide IP-3 showing the most promising results. These findings suggest that polysaccharides from mushroom fermentation could have potential health benefits and could be developed into medicinal supplements.

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A New Exopolysaccharide from a Wood-Decaying Fungus Spongipellis borealis for a Wide Range of Biotechnological Applications

Researchers isolated and studied a new polysaccharide from the wood-decaying mushroom Spongipellis borealis. This polysaccharide is composed mainly of glucose, galactose, and mannose sugars and acts as a natural stabilizer for important enzymes used in biotechnology. When this polysaccharide is added to enzyme preparations, it significantly improves their stability and performance under various conditions, making it promising for industrial and medical applications.

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