molecular mechanisms

Special Issue: Marine-Derived Compounds Applied in Cardiovascular Disease

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This collection of studies explores how compounds from ocean sources like seaweed, fish, shrimp, and microalgae can help protect heart health and prevent cardiovascular diseases. Researchers examined various marine ingredients and found they can reduce inflammation, lower cholesterol, reduce blood pressure, and prevent blood clots. The findings suggest that marine-derived products could become safer, more affordable alternatives or complements to current heart disease medications while supporting sustainable ocean resource use.

The Potential of Mushroom Extracts to Improve Chemotherapy Efficacy in Cancer Cells: A Systematic Review

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This systematic review examines how mushroom extracts can make chemotherapy more effective at treating cancer, particularly by helping overcome cancer cells’ resistance to drugs. Researchers found that various mushroom species contain compounds that work together with chemotherapy drugs to kill cancer cells more effectively through different cellular mechanisms. The results suggest mushroom extracts could be a promising natural complement to conventional cancer treatments, though more research is needed before they can be used clinically.

Integration of physio-biochemical, biological and molecular approaches to improve heavy metal tolerance in plants

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Heavy metals in soil can poison plants and damage crops, reducing food safety. Plants have natural defense systems that can be strengthened through adding minerals like silicon and boron, applying plant hormones, using specially designed nanoparticles, and improving soil quality. This review explains how different combinations of these approaches can help plants survive in contaminated soil and produce safer food.

Endophytic Beauveria spp. Enhance Tomato Growth and Resistance to Botrytis cinerea via Transcriptomic Regulation

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Researchers tested five types of beneficial fungi from the Beauveria genus to see if they could help tomato plants grow better and resist gray mold disease. They found that all five species could live inside tomato plants and help them grow taller. Most importantly, the fungus Beauveria brongniartii completely protected plants from gray mold infection. By examining which genes were activated in the plants, scientists discovered that these fungi boost the plant’s natural defense systems while also improving photosynthesis.

Heavy Metal-Contaminated Soils and Gastric Cancer Risk: Molecular Insights and the Relevance of a One Health Perspective

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Heavy metals like cadmium, arsenic, and lead contaminate agricultural soils and accumulate in crops such as rice and vegetables, which people consume as part of their daily diet. These metals damage stomach cell DNA and trigger inflammation, increasing cancer risk, especially when combined with bacterial infections like H. pylori. A comprehensive approach monitoring soil quality, crop safety, and human health together can help prevent this disease and protect communities from contamination.

Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

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This comprehensive review examines over 270 bioactive compounds from edible and medicinal mushrooms, showing they have remarkable potential to treat various diseases. These mushroom-derived substances demonstrate effectiveness against cancer, diabetes, inflammation, and infections while having fewer side effects than conventional drugs. Families like reishi and shiitake mushrooms are particularly rich sources of these healing compounds. The research suggests mushrooms are valuable natural resources for developing new therapeutic treatments.

Dietary Phytochemicals in Cardiovascular Disease Prevention and Management: A Comprehensive Review

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This review examines how plant-based compounds called phytochemicals can help prevent and manage heart disease. These compounds, found in foods like berries, nuts, tea, garlic, and whole grains, work through multiple mechanisms including reducing inflammation, lowering cholesterol, and improving blood vessel function. The review highlights that while pharmaceutical treatments exist, dietary approaches using phytochemical-rich foods offer a cost-effective and sustainable way to support heart health.

Therapeutic and Preventive Potential of Plant-Derived Antioxidant Nutraceuticals

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This comprehensive review explores how compounds found in plants can protect our bodies from harmful damage caused by oxidative stress, which is linked to aging and various diseases. Plant-based foods rich in antioxidants like berries, leafy greens, and olive oil contain special molecules that can help prevent cancer, heart disease, diabetes, and other chronic conditions. The review highlights that these natural compounds work through multiple beneficial mechanisms beyond just antioxidant activity, making plant-based diets an effective strategy for maintaining health and preventing disease.

The Therapeutic Effect and Mechanism of Traditional Chinese Medicine in Type 2 Diabetes Mellitus and Its Complications

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Traditional Chinese Medicine uses various herbs and plant compounds to treat Type 2 diabetes by improving how the body controls blood sugar and protects the pancreas. Many common TCM herbs like ginseng, rehmannia, and coptis work through natural mechanisms that reduce inflammation, protect cells from damage, and improve how the body uses insulin. Research shows TCM may also help prevent or reduce diabetes-related complications affecting the eyes, kidneys, and nerves. These herbal treatments offer potential benefits with fewer side effects compared to conventional medications.

A Systematic Review on Important Risk Factors and Possible Involved Mechanisms of Medicinal Plants on Nonalcoholic Fatty Liver Disease

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This comprehensive review examined 43 medicinal plants that can help prevent and treat fatty liver disease (NAFLD), which is increasingly common in developed countries. Most of these plants work by reducing cholesterol and triglycerides, helping with weight management, improving blood sugar control, and lowering blood pressure. The plants contain natural compounds like flavonoids and polyphenols that reduce inflammation and oxidative stress in the liver. Using these herbal supplements alongside other lifestyle changes may offer a promising natural approach to managing NAFLD and its related conditions.

Research Keyword: molecular mechanisms