Research Keyword: molecular identification

Isolation and characterization of a new Leptobacillium species promoting tomato plant growth

Scientists discovered a new type of beneficial fungus living inside tomato plant roots that helps the plants grow better and produce more nutritious fruit. This fungus, called Leptobacillium sp., makes plant hormones and special compounds that help tomato plants absorb nutrients more effectively. When tomato seeds were treated with this fungus, the plants grew taller and produced fruits with higher levels of lycopene, a beneficial compound. This discovery could help farmers grow better tomatoes using nature’s own microorganisms instead of relying on chemical treatments.

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Integrating Machine Learning and Molecular Methods for Trichophyton indotineae Identification and Resistance Profiling Using MALDI-TOF Spectra

A new type of fungus called Trichophyton indotineae is causing stubborn skin infections that don’t respond well to standard antifungal treatments. Researchers used advanced laboratory techniques combined with computer analysis to better identify this fungus from MALDI-TOF spectra, which is a quick fingerprinting method for microorganisms. The study showed that machine learning could accurately distinguish this problematic fungus from similar species and found specific markers that could help clinics detect it faster, potentially improving patient treatment outcomes.

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Evaluating the effectiveness of Pisolithus tinctorius in enhancing the Eucalyptus’ resistance to salt stress

Scientists isolated a beneficial fungus called Pisolithus tinctorius that can help eucalyptus trees survive in salty soil. When seedlings were treated with this fungus, they grew much better and were more resistant to salt stress compared to untreated plants. This discovery could help restore salt-damaged lands and make eucalyptus plantations more productive in challenging environments.

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Schizophyllum radiatum: An uncommon culprit of invasive fungal rhinosinusitis in an immunocompetent patient – A case report from India

A 32-year-old healthy woman in India developed a serious fungal infection in her sinuses caused by an extremely rare fungus called Schizophyllum radiatum. Standard laboratory tests could not identify the fungus due to its unusual characteristics, so doctors used advanced DNA sequencing to confirm the diagnosis. After surgery to remove the infected material and treatment with antifungal medication, the patient fully recovered, marking this as likely the first documented case of this type of infection in India.

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Candidemia due to Candida lambica in a neutropenic oncology patient: A rare case report

A 56-year-old cancer patient developed a rare blood infection caused by an unusual yeast called Candida lambica while receiving chemotherapy. Despite taking antifungal medication for prevention, the patient developed a serious fever and low white blood cell count. Doctors identified the infection through genetic testing and treated it with a different antifungal drug called voriconazole, which successfully cleared the infection.

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Gastrointestinal and Intra-Abdominal Mucormycosis in Non-Haematological Patients—A Comprehensive Review

This review examines a serious but rare fungal infection called mucormycosis that affects the stomach and intestines. The infection most commonly occurs in patients with diabetes, those who have received organ transplants, or those in intensive care units. Diagnosis can be difficult because symptoms are non-specific, but prompt treatment with antifungal medications and surgery when possible significantly improves survival rates. Early recognition and rapid diagnosis are critical for patients to have the best outcomes.

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Overexpression of efflux pump and biofilm associated genes in itraconazole resistant Candida albicans isolates causing onychomycosis

This study examined why some fungal nail infections caused by Candida albicans don’t respond to itraconazole treatment. Researchers found that resistant fungi have higher levels of genes that pump the antifungal drug out of their cells and genes that help them form protective biofilm layers. These findings suggest that combining itraconazole with drugs that block these pumps or disrupt biofilms could be more effective for treating stubborn fungal nail infections.

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Morpho-molecular analyses reveal two novel species and two new records of Dictyosporiaceae (Pleosporales) from Dulongjiang River in northwestern Yunnan Province, China

Scientists discovered and identified four new or newly recorded fungal species from a river in China’s Yunnan Province. These fungi, belonging to the Dictyosporiaceae family, were found growing on submerged wood in the Dulongjiang River. By combining detailed microscopic observation with genetic analysis, researchers confirmed two completely new species and two species not previously recorded in this region, expanding our understanding of freshwater fungal diversity.

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Identification, characterization, antimicrobial activity and biocontrol potential of four endophytic fungi isolated from Amazonian plants

Scientists isolated four types of fungi living inside the leaves of medicinal plants from the Amazon region of Bolivia. These fungi produce natural compounds that kill harmful bacteria and fungi that damage potato crops. The findings show promise for developing natural alternatives to synthetic pesticides and antibiotics for agricultural and medical applications.

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Epidemiology of mucormycosis in COVID-19 patients in northwest Iran: Rhizopus arrhizus as the predominant species

This study found that COVID-19 patients in northwestern Iran who received high-dose steroid treatment developed serious fungal infections called mucormycosis. The infection was caused primarily by a fungus called Rhizopus arrhizus and affected mainly the sinuses and brain. The steroids used to treat COVID-19 weakened patients’ immune systems and triggered diabetes, both of which made them vulnerable to this dangerous fungal infection.

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