Research Keyword: molecular identification

Coexistence of Malassezia Species and Microsporum canis in the Lesions of Adult with Tinea Capitis

A 60-year-old woman developed unusual hair loss and scalp inflammation that looked like dandruff but was actually a fungal infection caused by multiple fungi working together. Doctors found three different fungi in her scalp samples: one dermatophyte and two Malassezia species. Lab experiments showed that the Malassezia fungi actually helped the main disease-causing fungus grow better, which explains why the condition looked different from typical cases. After three months of antifungal medication, her symptoms cleared and her hair grew back.

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Essential Oils as an Antifungal Alternative to Control Several Species of Fungi Isolated from Musa paradisiaca: Part II

Bananas often develop fungal infections during storage that reduce their quality. Researchers tested whether essential oils from common herbs and spices like cinnamon, clove, and oregano could prevent these fungal infections. The study found that cinnamon, clove, and oregano oils effectively stopped fungal growth at higher concentrations, offering a natural alternative to chemical fungicides that could help keep bananas fresh longer without synthetic chemicals.

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Polyphasic characterization and mating type allele distribution of Monilinia laxa in Iranian stone fruit orchards

Brown rot is a serious fungal disease affecting fruit trees like apricots, cherries, and plums. Researchers collected over 400 fungal isolates from Iranian fruit orchards and identified two main species causing the disease, with one species being far more common. By developing new genetic tests, scientists discovered both male and female forms of the fungi exist in equal proportions, suggesting the disease could evolve through sexual reproduction, which has important implications for managing the disease in orchards.

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Candida vulturna, the Next Fungal Menace? A Narrative Review

Candida vulturna is a newly identified fungus that causes serious bloodstream infections, particularly in newborns and hospitalized patients in tropical regions. Unlike many common fungal infections, it resists several antifungal medications, though it remains susceptible to certain antibiotics called echinocandins. Scientists have documented 94 cases worldwide, including three hospital outbreaks, and the infection has a relatively low death rate of 18%. Accurate identification requires genetic testing since standard hospital laboratory tests often misidentify this pathogen.

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Five new species of Inosperma from China: Morphological characteristics, phylogenetic analyses, and toxin detection

Researchers in China identified five new species of poisonous mushrooms called Inosperma and tested them for dangerous toxins. They used advanced laboratory methods to detect four types of neurotoxins that can cause serious health problems when people eat these mushrooms. Each species contained different combinations of toxins, with some containing none and others containing one or more toxic compounds that affect the nervous system.

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The first report of rhinosinusitis by Rhizopus delemar in a patient with severe COVID-19 in Iran: a case report

A 63-year-old man hospitalized with COVID-19 developed a serious fungal sinus infection caused by a rare mold called Rhizopus delemar. Despite surgery to remove infected tissue and treatment with antifungal medication amphotericin B, the infection spread and the patient died after five weeks. This was the first documented case of this particular mold causing sinus infection in a COVID-19 patient in Iran, highlighting how severe fungal infections can occur as dangerous complications of COVID-19.

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Localized Versus Diffuse Corneal Invasion in Fungal Keratitis: Histological Insights from Candida albicans and Fusarium falciforme

This study compared how two types of fungi invade the cornea of the eye. Candida albicans, a yeast, stayed localized to where it entered the eye and was easier to control surgically. In contrast, Fusarium falciforme, a mold, spread aggressively throughout the entire cornea and was much harder to treat. Understanding these different invasion patterns helps explain why some fungal eye infections are more difficult to manage than others.

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Acute fungal endometritis in women with abnormal uterine bleeding: Clinical and microbiological insights

This study examined a rare fungal infection of the uterus called fungal endometritis that causes abnormal bleeding and discomfort in women. Researchers found that about 12% of women with unexplained abnormal bleeding had this fungal infection, which was caused by different species of Candida yeast. A simple test using vaginal swabs was not effective for diagnosis; instead, doctors needed to take samples directly from the uterine lining. Treatment with an antifungal medication called voriconazole combined with surgical cleaning was successful in all cases studied.

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Disseminated Lichtheimia ramosa infection in a Japanese Black calf

A young beef calf developed severe diarrhea and fever that did not respond to multiple antibiotics. The calf had an underdeveloped immune system (missing thymus gland) and was treated with many antibiotics and steroids, which weakened its immune system further. After death, examination revealed the calf had a widespread fungal infection caused by Lichtheimia ramosa in the liver and digestive tract, representing the first documented case of this type in Japanese Black cattle.

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Biocontrol Potential of Bacillus velezensis RS65 Against Phytophthora infestans: A Sustainable Strategy for Managing Tomato Late Blight

Researchers tested 30 soil bacteria from tomato roots to find natural disease fighters. They discovered that Bacillus velezensis RS65, a beneficial bacterium, effectively prevents tomato late blight by producing enzymes and toxins that kill the fungal pathogen. In greenhouse tests, plants treated with RS65 had half the disease severity compared to untreated plants, suggesting this bacteria could replace chemical fungicides in sustainable tomato farming.

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