Research Keyword: Mixed infection

Primary cutaneous mixed infection with Cryptococcus uniguttulatus and Mycobacterium tuberculosis

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A 43-year-old man had persistent facial skin lesions for seven years that initially appeared to be fungal infection caused by Cryptococcus uniguttulatus. Standard antifungal treatments failed to completely cure the condition. Advanced genetic testing revealed the lesions were actually caused by two simultaneous infections: the fungus and tuberculosis bacteria. Once both infections were properly identified and treated with appropriate medications, the skin lesions finally healed.

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Mixed Infection With Aspergillosis and Actinomycosis in the Maxillary Sinus: A Case Report

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A 74-year-old woman with diabetes and rheumatoid arthritis developed a rare dual infection in her maxillary sinus (a cavity above the teeth) caused by both a fungus (Aspergillus) and bacteria (Actinomyces). Imaging tests initially suggested only fungal infection, but surgery and tissue examination revealed both organisms were present. The patient was successfully treated with surgical removal of the infected material combined with antibiotics, leading to complete recovery.

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Mixed Infection With Aspergillosis and Actinomycosis in the Maxillary Sinus: A Case Report

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A 74-year-old woman had a purulent nasal discharge for 1.5 years caused by two different infections occurring simultaneously in her maxillary sinus: aspergillosis (a fungal infection) and actinomycosis (a bacterial infection). Imaging initially suggested only a fungal ball, but pathological examination revealed both organisms were present. The patient was successfully treated with surgical removal of the infected material followed by antibiotic therapy.

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A Case of Sphenoid Sinusitis With Epidural Abscess due to Fungal Infection and Mixed Infection With Eikenella corrodens and Aggregatibacter segnis

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A 60-year-old woman developed a severe headache caused by a fungal and bacterial infection in her sphenoid sinus (located deep in the skull). The infection spread intracranially, creating an abscess. Doctors used imaging scans to diagnose the problem, performed surgery to drain the infection and remove the fungal material, and treated the patient with antibiotics. The patient recovered completely with no recurrence after four years.

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First report of Stemphylium lycopersici keratitis, a complex corneal infection case

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A 66-year-old man developed a severe corneal infection from a stone chip injury that didn’t improve with standard antibiotics. Doctors discovered the infection was caused by a rare plant fungus called Stemphylium lycopersici, combined with a herpes virus. Using advanced genetic testing (mNGS) to identify the exact pathogens, they prescribed targeted antifungal and antiviral medications along with a corneal transplant, successfully healing the infection and preserving his vision.

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Clinical insights into mixed Candida and bacterial bloodstream infections: a retrospective cohort study

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This study found that when both Candida fungus and bacteria are present together in a patient’s bloodstream, the outcome is much more serious than when only Candida is present. Among patients with these mixed infections, over 60% died within 30 days compared to about 52% for those with only Candida. The research shows that giving the right antibiotics early and following proper treatment guidelines can significantly improve survival chances in these severe, life-threatening infections.

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Primary cutaneous mixed infection with Cryptococcus uniguttulatus and Mycobacterium tuberculosis

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A 43-year-old man had a persistent facial rash that didn’t improve with standard antifungal treatments. Doctors initially found a fungal infection called Cryptococcus uniguttulatus using culture tests. However, advanced molecular testing (DNA sequencing) revealed he also had a tuberculosis infection in the same skin lesion. Once both infections were treated with appropriate medications, the patient’s rash finally improved. This case shows that sometimes people can have multiple infections at the same location and that newer diagnostic methods are important for finding these hidden infections.

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