minimum inhibitory concentrations

Neosartorya udagawae pulmonary infection requiring a surgical treatment in a paediatric haematopoietic progenitor cell recipient

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A three-year-old boy with leukemia received a bone marrow transplant and developed a serious fungal lung infection caused by Neosartorya udagawae, a rare fungal pathogen. Despite receiving multiple antifungal medications at appropriate doses, the infection continued to worsen and spread in his lungs. Doctors ultimately had to surgically remove the infected portion of his lung (left upper lobe) to successfully treat the infection, and the child recovered completely without recurrence after three years of follow-up.

Saksenaea oblongispora Rhinosinusitis in Advanced HIV: A Rare and Lethal Mucormycosis

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A 32-year-old man with advanced HIV developed a severe fungal infection of his sinuses caused by a rare fungus called Saksenaea oblongispora, which typically doesn’t affect people with HIV. The patient presented with severe facial swelling that rapidly worsened, and despite doctors identifying the fungus through biopsies and lab tests, he did not receive antifungal treatment or surgery before his condition became critical. This is the first case of this particular fungal infection documented in sub-Saharan Africa and in HIV patients, highlighting how dangerous this rare infection can be and how challenging it is to diagnose quickly enough to save lives.

Candidemia due to Candida lambica in a neutropenic oncology patient: A rare case report

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A 56-year-old cancer patient developed a serious bloodstream infection caused by a rare yeast called Candida lambica despite taking antifungal medications. Doctors identified the infection using genetic sequencing and found that the organism was sensitive to a different antifungal drug called voriconazole. After switching medications and removing the patient’s central line, the infection cleared up. This case demonstrates the importance of accurately identifying fungal infections and testing which medications work best against them.

First isolation of Prototheca bovis from a bottlenose dolphin (Tursiops truncatus)

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A 13-year-old bottlenose dolphin at a Japanese aquarium developed a stomach infection caused by Prototheca bovis, a type of alga rarely found in marine animals. The dolphin initially received treatment with itraconazole for a suspected fungal infection, but this was ineffective. When doctors identified the actual culprit as P. bovis through genetic testing, they switched to fos-ravuconazole, which successfully resolved the infection and returned the dolphin to good health.

Research Keyword: minimum inhibitory concentrations

Neosartorya udagawae pulmonary infection requiring a surgical treatment in a paediatric haematopoietic progenitor cell recipient

Saksenaea oblongispora Rhinosinusitis in Advanced HIV: A Rare and Lethal Mucormycosis

Candidemia due to Candida lambica in a neutropenic oncology patient: A rare case report

First isolation of Prototheca bovis from a bottlenose dolphin (Tursiops truncatus)