Microbiome composition

Modulation of gut microbiome in response to the combination of Escherichia coli Nissle 1917 and sugars: a pilot study using host-free system reflecting impact on interpersonal microbiome

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This study examined how a beneficial bacteria called Escherichia coli Nissle 1917 combined with different types of sugar affects gut bacteria. Researchers found that the effectiveness of these treatments depends heavily on each person’s unique starting microbiota composition, which is shaped by their diet, lifestyle, and health status. The results show that one-size-fits-all probiotic treatments don’t work equally for everyone, and doctors should personalize treatments based on an individual’s existing gut bacteria profile.

Quercetin hybrid-hydrogel microparticles modulate gut microbiota and improve memory in an antibiotic-induced dysbiosis rat model

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A natural quercetin supplement formulated with fenugreek fiber was tested on rats with antibiotic-damaged gut bacteria. The supplement successfully restored healthy gut bacteria diversity, reduced gut inflammation, and improved memory performance. These benefits likely work through the gut-brain connection, where healthy bacteria produce beneficial chemicals that support brain function and reduce inflammation.

Interventions targeting the gut-liver axis: A potential treatment strategy for metabolic dysfunction-associated steatotic liver disease

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Your gut bacteria play a crucial role in liver health. When harmful bacteria build up in your gut, they can trigger liver inflammation and fat accumulation, leading to fatty liver disease. Researchers found that simple lifestyle changes like intermittent fasting, eating certain foods that feed good bacteria, and maintaining a healthy diet can restore healthy gut bacteria, strengthen your intestinal barrier, and reduce liver disease. This gut-focused approach could offer new ways to prevent and treat fatty liver disease beyond current treatments.

The Effect of Fungal Nutraceutical Supplementation on Postoperative Complications, Inflammatory Factors and Fecal Microbiota in Patients Undergoing Colorectal Cancer Surgery with Curative Intent: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial

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Researchers tested whether a supplement made from nine different medicinal mushroom types could reduce complications after colorectal cancer surgery. While the supplement didn’t significantly reduce overall complications, it did appear to boost immune function in patients undergoing traditional surgery and favorably changed the composition of gut bacteria. The supplement was well-tolerated with no serious side effects.

From Microbes to Myocardium: A Comprehensive Review of the Impact of the Gut-Brain Axis on Cardiovascular Disease

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Your gut bacteria play a surprising role in heart health through a communication network called the gut-brain axis. When the balance of gut bacteria is disrupted (dysbiosis), it can lead to heart disease, high blood pressure, and clogged arteries. Beneficial bacteria produce helpful compounds like short-chain fatty acids that reduce inflammation and protect blood vessels, while harmful bacteria produce compounds that increase heart disease risk. Simple interventions like eating more fiber, taking probiotics, managing stress, and exercising can help maintain a healthy gut microbiome and improve heart health.

Glycosylation and sugar variations in tyrosol yield promising prebiotic-like effects

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This study tested whether chemically modified versions of tyrosol, a natural compound found in olives and red wine, could boost beneficial gut bacteria better than the original form. Researchers gave mice three different versions: plain tyrosol, natural salidroside (tyrosol with glucose attached), and a lab-created version with galactose attached instead. The galactose version worked best, promoting the most beneficial bacteria like Bifidobacteria and reducing harmful bacteria, potentially offering health benefits similar to prebiotic supplements.

Dietary Intake of Phytochemicals, Gut Microbiota, and Appetite Control

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This research editorial highlights how plant-based foods rich in phytochemicals can improve gut health by promoting beneficial bacteria growth and supporting communication between the gut and brain. These dietary interventions show promise in helping control appetite, improve metabolism, and reduce the risk of diseases like obesity and type 2 diabetes. The studies suggest that personalized nutrition approaches based on individual microbiome profiles could offer more effective disease prevention and health maintenance strategies.

Potential Protective Role of Amphibian Skin Bacteria Against Water Mold Saprolegnia spp

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Frog populations are declining due to various diseases and environmental challenges. This research discovered that bacteria living on frog skin can protect against harmful water molds called Saprolegnia that attack amphibian eggs. Scientists found that different types of bacteria, particularly Bacillus species, can inhibit the growth of these water molds. The protective effect was strongest in nutrient-poor conditions similar to natural water environments, suggesting that the bacterial symbiosis with frogs may be an important defense mechanism.

Potential Protective Role of Amphibian Skin Bacteria Against Water Mold Saprolegnia spp.

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Researchers discovered that bacteria living on frog skin can protect against a dangerous water mold called Saprolegnia that kills amphibian eggs and young tadpoles. They tested 196 different bacteria from frogs in Portugal and found that certain bacteria, especially Bacillus species, could stop the mold from growing. Interestingly, these bacteria worked best in clean water environments with fewer nutrients, similar to natural pond conditions, suggesting nature has built-in protections for amphibians.

Gut fungal profiles reveal phylosymbiosis and codiversification across humans and nonhuman primates

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Researchers studied fungal communities in the guts of humans and various primates to understand how these fungi evolved alongside their hosts. They discovered that more closely related primate species have more similar fungal communities, and that some fungi show signs of evolving together with primates over millions of years. These findings suggest that gut fungi are long-term partners with their hosts rather than temporary travelers from diet alone.

Research Keyword: Microbiome composition