Research Keyword: microbiome

Dietary live microbe intake and its association with Parkinson’s disease in American adults: an NHANES analysis (1999–2018)

This study found that eating more foods rich in live microbes—like fermented products (yogurt, kimchi) and fresh fruits and vegetables—is associated with lower rates of Parkinson’s disease in American adults. The protective effect was strongest in people without obesity. The live microbes appear to work by maintaining a healthy gut environment, reducing inflammation, and protecting nerve cells from damage. This suggests that regular consumption of microbe-rich foods from nature might be a simple, inexpensive way to help prevent or slow Parkinson’s disease.

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Prospective Comparative Study of an Oral Synbiotic and a Myoinositol-Based Herbal Supplement in Modifying Hormone Levels and the Gut Microbiome in Non-cystic Acne

This study tested two supplements for treating non-cystic acne: one containing probiotics and herbs, and another based on myoinositol and medicinal plants. Both supplements significantly reduced acne lesions and improved gut health by increasing beneficial bacteria and beneficial fatty acids produced by these bacteria. The myoinositol-based supplement also reduced hormone precursors related to acne development. These findings suggest that supporting gut health may be an effective way to treat acne.

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Prebiotics and Probiotics Supplementation in Pigs as a Model for Human Gut Health and Disease

Pigs are excellent models for studying human digestive health because their gut anatomy and function closely resemble humans. This review shows that prebiotics (special food compounds) and probiotics (beneficial bacteria) can improve gut health and strengthen the intestinal barrier in both healthy pigs and those with infections. These findings suggest that similar treatments might help prevent and treat digestive diseases in humans.

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Investigating the Knowledge of Prebiotics, Probiotics, and Synbiotics That May Help to Improve the Gut-Organ Axis Function in Middle-Aged and Older Adults

This study examined what middle-aged and older adults know about probiotics, prebiotics, and synbiotics—special food components that can improve gut health. Researchers found that many people had little knowledge about these products, even though they may help with various health conditions including heart disease and mental health. After giving people an educational information sheet about gut biotics, their knowledge significantly improved, suggesting that simple education can help people make better choices about their digestive health.

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Biosecurity Assessments for Emerging Transdisciplinary Biotechnologies: Revisiting Biodefense in an Age of Synthetic Biology

This article examines how scientists and policymakers are working to ensure that powerful new biotechnology tools are used safely and securely. As genetic engineering and artificial intelligence become more accessible, frameworks are needed to identify potential risks while allowing beneficial research to continue. The authors discuss three emerging areas—microbiome therapies, biohybrid materials, and AI applications—and explain how existing safety frameworks may need updating to address new types of risks beyond traditional biological weapons concerns.

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Geographic variation in fungal diversity associated with leaf spot symptoms of Coffea arabica in Yunnan, China

Researchers studied the different types of fungi found on coffee plant leaves in two regions of Yunnan, China. They discovered that the mountainous areas of Pu’er had more harmful fungi causing leaf spot disease, while the tropical lowlands of Xishuangbanna had more beneficial fungi that could naturally control pests. This information helps coffee farmers choose better disease management strategies based on their location’s unique environmental conditions.

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Supplementation in mushroom crops and its impact on yield and quality

Mushroom farmers can increase their harvest and improve mushroom quality by adding nutritional supplements to the growing medium. These supplements can be made from common agricultural waste products like grain bran and soybean meal, making them affordable and environmentally friendly. New research shows that beneficial bacteria and fungi might also boost mushroom production, offering sustainable alternatives to traditional chemical supplements.

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Mycelial Beehives of HIVEOPOLIS: Designing and Building Therapeutic Inner Nest Environments for Honeybees

Scientists created experimental beehives made from living mushroom mycelium (the root structure of mushrooms) combined with 3D-printed scaffolds. These hives are designed to keep bees warmer while providing natural antimicrobial compounds that protect them from diseases. The research combines digital design technology with biology to create homes that mimic the natural tree cavities where wild honeybees live, potentially making them healthier and more resilient to climate change and diseases.

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Insights into microbiome-triterpenoid correlation in Poria cocos via comparative analysis of sclerotial and soil microenvironments

Researchers discovered that the medicinal fungus Poria cocos creates its own specialized microbial environment in its underground structure that is closely linked to the production of pachymic acid, a compound with anti-cancer and immune-boosting properties. By comparing the microbes living in the fungus versus surrounding soil, they found specific beneficial bacteria and fungi that thrive in the fungus but are rare in soil. This discovery could help improve cultivation techniques to produce higher quality medicinal fungi with more therapeutic compounds.

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