Research Keyword: microbiology

Miniaturized high-throughput conversion of fungal strain collections into chemically characterized extract libraries for antimicrobial discovery

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Scientists developed a fast, automated method called FLECS-96 to screen hundreds of fungal species for antimicrobial compounds in a small 96-well plate format. The method combines fungal culture, chemical extraction, and analysis to identify promising candidates against resistant bacteria like Staphylococcus aureus. The team successfully identified two bioactive compounds from the fungi tested. This innovation could significantly speed up the discovery of new antibiotics to combat antibiotic-resistant infections.

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Utility of MALDI-ToF MS for Recognition and Antifungal Susceptibility of Nannizzia, an Underestimated Group of Dermatophytes

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Nannizzia species are soil-dwelling fungi that increasingly cause stubborn skin, nail, and hair infections in humans and animals. This study tested two laboratory methods for identifying these fungi and measured their sensitivity to eight antifungal drugs. The faster liquid-based method was slightly more accurate (67%) than the traditional culture method (62%), though neither method could identify six very rare species. Terbinafine emerged as the most effective antifungal treatment in laboratory tests.

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Physicochemical Properties and Volatile Profile of Chito: A Traditional Dry-Cured Goat Meat Product

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Chito is a traditional Mexican goat meat product that comes in two forms: one for immediate eating and one pressed for sale in other regions. Researchers studied these products over three years and found that the pressed version becomes harder, saltier, and develops more of the rancid flavors associated with fat breakdown. Despite these differences, both versions maintain safe bacteria levels through the natural preservation from salt and sun-drying.

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