Research Keyword: MFS transporters

Inhibitory Effect and Mechanism of Dryocrassin ABBA Against Fusarium oxysporum

Researchers found that dryocrassin ABBA, a compound from a traditional East Asian fern, can effectively kill the fungus that causes potato rot disease. The compound damages the fungus by increasing harmful reactive oxygen species and disrupting the fungus’s ability to break down plant cell walls. This natural substance could potentially replace synthetic chemical fungicides, offering a safer and more environmentally friendly way to protect potatoes from disease.

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Exposure to Tebuconazole Drives Cross-Resistance to Clinical Triazoles in Aspergillus fumigatus

Farmers use a fungicide called tebuconazole to protect crops, but this chemical is similar to medicines doctors use to treat serious fungal infections in patients. A new study shows that when the fungus Aspergillus fumigatus is exposed to tebuconazole, it becomes resistant not just to this pesticide, but also to the clinical antifungal drugs used in hospitals. The fungus develops resistance mechanisms that allow it to survive high doses of these medications. This research highlights an important public health concern: the overuse of similar chemicals in agriculture can undermine our ability to treat dangerous fungal infections in people.

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