metagenomic next-generation sequencing

Naganishia albidus Causing Perioral Cutaneous Infection: A Rare Case Easily Misdiagnosed

mycolabadmin

A 37-year-old man developed an unusual fungal skin infection around his mouth caused by Naganishia albidus, a rare yeast. He was initially misdiagnosed with eczema and his condition worsened with wrong treatment. Advanced fungal testing techniques helped identify the correct organism, and after six weeks of antifungal medication (both oral and topical), his skin completely cleared. This case shows why doctors need to consider rare fungal infections when skin problems don’t respond to typical treatments.

Extensive erythematous plaques of fungal origin in an overseas student: Cutaneous manifestation of coccidioidomycosis

mycolabadmin

A 21-year-old student studying in Arizona developed unusual skin rashes months after returning to China. Doctors had difficulty diagnosing the condition because it lacked typical symptoms of the fungal infection coccidioidomycosis. By using multiple diagnostic methods including DNA sequencing and fungal culture, they identified the infection as caused by Coccidioides posadasii. When the initial antifungal drug didn’t work, testing showed the fungus was resistant, so they switched to a different antifungal called voriconazole, which successfully cured the infection after 12 months.

Naganishia albidus Causing Perioral Cutaneous Infection: A Rare Case Easily Misdiagnosed

mycolabadmin

A 37-year-old construction worker developed unusual scaling and itchy sores around his mouth that worsened despite treatment for eczema. Doctors eventually discovered the infection was caused by a rare yeast fungus called Naganishia albidus, which is almost never seen in healthy people. Using advanced laboratory tests and antifungal medications taken by mouth and applied to the skin, the infection completely cleared within six weeks.

First report of Stemphylium lycopersici keratitis, a complex corneal infection case

mycolabadmin

A 66-year-old man developed a severe corneal infection from a stone chip injury that didn’t improve with standard antibiotics. Doctors discovered the infection was caused by a rare plant fungus called Stemphylium lycopersici, combined with a herpes virus. Using advanced genetic testing (mNGS) to identify the exact pathogens, they prescribed targeted antifungal and antiviral medications along with a corneal transplant, successfully healing the infection and preserving his vision.

Research Keyword: metagenomic next-generation sequencing

Naganishia albidus Causing Perioral Cutaneous Infection: A Rare Case Easily Misdiagnosed

Extensive erythematous plaques of fungal origin in an overseas student: Cutaneous manifestation of coccidioidomycosis

Naganishia albidus Causing Perioral Cutaneous Infection: A Rare Case Easily Misdiagnosed

First report of Stemphylium lycopersici keratitis, a complex corneal infection case