Research Keyword: metagenomic analysis

Quercetin hybrid-hydrogel microparticles modulate gut microbiota and improve memory in an antibiotic-induced dysbiosis rat model

A natural quercetin supplement formulated with fenugreek fiber was tested on rats with antibiotic-damaged gut bacteria. The supplement successfully restored healthy gut bacteria diversity, reduced gut inflammation, and improved memory performance. These benefits likely work through the gut-brain connection, where healthy bacteria produce beneficial chemicals that support brain function and reduce inflammation.

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Beneficial bacterial-Auricularia cornea interactions fostering growth enhancement identified from microbiota present in spent mushroom substrate

Researchers discovered that certain beneficial bacteria, particularly Pseudonocardia mangrovi, can significantly boost the growth of wood ear mushrooms (Auricularia cornea) through laboratory studies. By analyzing the microscopic communities in spent mushroom substrates from high-yielding versus low-yielding farms, they identified bacteria that promote mushroom growth through multiple mechanisms. Co-cultivation experiments and protein analysis revealed these bacteria work synergistically by helping mushrooms break down nutrients and produce growth-enhancing compounds. This research can help farmers select beneficial microbes to improve mushroom yields and profitability.

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Biodegradation of synthetic organic pollutants: principles, progress, problems, and perspectives

This comprehensive review explains how bacteria naturally break down synthetic pollutants in our environment through various mechanisms. Scientists use advanced tools like gene sequencing and computer analysis to identify which bacteria degrade specific pollutants, how quickly they work, and what intermediate products form. Understanding these bacterial degradation pathways helps us develop better strategies to clean up contaminated water and soil in an environmentally friendly way.

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Dynamic succession of microbial compost communities and functions during Pleurotus ostreatus mushroom cropping on a short composting substrate

Researchers studied how bacteria and fungi work together when growing oyster mushrooms on composted materials. They found that certain bacteria, particularly Actinomycetales, increase in abundance as mushrooms grow and help break down tough plant materials like cellulose. These bacteria actually help the mushroom grow better, suggesting a cooperative relationship rather than competition. This knowledge could help improve mushroom production efficiency.

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In vitro fermentation characteristics and prebiotic activity of herbal polysaccharides: a review

This review explores how plant-based polysaccharides from traditional herbs can benefit our health by feeding good bacteria in our gut. When these polysaccharides are fermented by our gut microbiota, they break down into smaller compounds that produce short-chain fatty acids, which have anti-inflammatory and immune-boosting effects. The research shows that different herbs have different structures that are recognized by specific beneficial bacteria, which suggests we can develop personalized functional foods tailored to promote specific health benefits.

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Marine-Derived Enterococcus faecalis HY0110 as a Next-Generation Functional Food Probiotic: Comprehensive In Vitro and In Vivo Bioactivity Evaluation and Synergistic Fermentation of Periplaneta americana Extract Powder

Scientists discovered a beneficial bacteria called Enterococcus faecalis HY0110 from bluefin tuna that could help protect gut health and fight harmful pathogens better than current probiotics. This marine bacteria produces important compounds like acetic acid that kill disease-causing bacteria, reduce inflammation in inflammatory bowel disease, and even slows cancer cell growth. When fermented with cockroach powder, it creates powerful health-boosting compounds that could make functional foods more effective for managing digestive diseases and supporting overall wellness.

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Effects of a biotechnologically produced Pleurotus sapidus mycelium on gut microbiome, liver transcriptome and plasma metabolome of broilers

Researchers tested whether mushroom mycelium (the root structure of mushrooms) grown in large bioreactors could be used as a supplement in chicken feed as a sustainable alternative to traditional ingredients. Over 5 weeks, broilers received feed with 0%, 2.5%, or 5% mushroom mycelium, with no negative effects on growth, digestion, or overall health observed. The study suggests that this biotechnologically produced mushroom biomass is a safe and potentially sustainable feed ingredient for poultry production.

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Differential composition of the pulmonary microbiome in HIV-positive versus HIV-negative patients with Pneumocystis jirovecii

This study compared lung infections in HIV-positive and HIV-negative patients who both had Pneumocystis jirovecii. Researchers found that HIV-positive patients had more diverse microorganisms in their lungs, particularly viruses, yet generally did better. HIV-negative patients had fewer types of microorganisms but worse outcomes. The findings suggest that the way a person’s immune system is weakened matters more than just having many germs present.

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Halotolerant Endophytic Fungi: Diversity, Host Plants, and Mechanisms in Plant Salt–Alkali Stress Alleviation

Salty and alkaline soil is destroying farmland worldwide, but special fungi living inside plants can help crops survive these harsh conditions. These fungi work like a team with plants, producing protective substances and helping plants manage salt and reduce damage from stress. Scientists reviewed 150 studies and found these fungi boost crop yields by 15-40%, offering a natural way to farm on degraded land without more chemicals.

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Detection of Pestalotiopsis abbreviata sp. nov., the Causal Agent of Pestalotiopsis Leaf Blight on Camellia japonica Based on Metagenomic Analysis

Researchers discovered a new fungal species called Pestalotiopsis abbreviata that causes leaf disease on Camellia japonica, an ornamental tree popular in Korea. Instead of using traditional time-consuming laboratory methods, they used advanced genetic sequencing (metagenomic analysis) to quickly identify the fungus among hundreds of other microbes living on the tree leaves. This new approach is faster and more accurate than old methods, making it easier to monitor and manage plant diseases in the future.

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