metabolomics – Page 12

Effects of a biotechnologically produced Pleurotus sapidus mycelium on gut microbiome, liver transcriptome and plasma metabolome of broilers

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Researchers tested whether mushroom mycelium grown using agricultural waste could be safely added to chicken feed. The mycelium, rich in beneficial compounds like β-glucans, was added to broiler diets at varying levels for 35 days. Results showed that chickens fed diets containing up to 5% mushroom mycelium performed just as well as control chickens, with no negative effects on health, digestion, or metabolism, suggesting this sustainable feed ingredient could help reduce competition between animal feed and human food.

A mass spectrometry-based strategy for investigating volatile molecular interactions in microbial consortia: unveiling a Fusarium-specific induction of an antifungal compound

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Scientists developed a new method to study how different fungi communicate and compete with each other through invisible chemical signals called volatile organic compounds. By growing three types of fungi together in a controlled setup, they discovered that Fusarium culmorum specifically produces a compound called γ-terpinene when in contact with other fungi. This compound acts as a natural antifungal agent, helping Fusarium fight off competing fungi. This research provides a blueprint for understanding complex fungal interactions in environments like human lungs and could eventually help diagnose or prevent fungal-related diseases.

Nontargeted metabonomics analysis of Scorias spongiosa fruiting bodies at different growth stages

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This study analyzed the chemical composition of Scorias spongiosa, an edible fungus, at different stages of growth using advanced laboratory techniques. Researchers found that the fungus contains beneficial compounds with antioxidant, anti-inflammatory, and other health-promoting properties. The study recommends harvesting the fungus at its earliest growth stage to preserve the most beneficial compounds for food and nutritional products.

Advances in Fungal Natural Products: Insights into Bioactivity and Therapeutic Potential

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Medicinal mushrooms and fungi contain powerful natural chemicals that can boost immunity, reduce inflammation, fight cancer, and protect the brain. Scientists are now better able to identify and study these compounds using advanced techniques, and some are being tested as supplements or alongside traditional medicines. This research shows that mushrooms could become important tools in treating diseases like inflammatory bowel disease, rheumatoid arthritis, and cancer.

Multi-Omics Analysis of Low-Temperature Fruiting Highlights the Promising Cultivation Application of the Nutrients Accumulation in Hypsizygus marmoreus

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Scientists studied how beech mushrooms develop during a special low-temperature fruiting process that requires a long waiting period. They discovered that amino acids (particularly arginine) and citric acid accumulate during this process, and that adding these compounds externally can speed up mushroom production by 10 days and increase yield by 10-15%. This research could help mushroom farmers reduce costs and time in cultivation.

Leucocalocybe mongolica inoculation enhances rice growth by reallocating resources from flavonoid defense to development via MYB/bHLH/WRKY networks

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A fungal strain called Leucocalocybe mongolica (LY9) can help rice plants grow bigger and healthier by improving how they use nutrients and sunlight. Interestingly, when plants grow better with this fungus, they produce fewer defensive compounds called flavonoids, but they still maintain some protective molecules. This research shows that the fungus helps plants decide to invest more energy in growth rather than defense, making it a promising natural fertilizer for farming.

Mushrooms Do Produce Flavonoids: Metabolite Profiling and Transcriptome Analysis of Flavonoid Synthesis in the Medicinal Mushroom Sanghuangporus baumii

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Researchers discovered that the medicinal mushroom Sanghuangporus baumii produces 81 different flavonoids, compounds known for their health benefits including antioxidant and anti-cancer properties. Using advanced genetic and chemical analysis, they identified the genes and processes responsible for this flavonoid production in mushrooms, which differs from how plants make these compounds. By increasing the activity of a key gene called PAL, they were able to boost flavonoid production in the mushroom. This discovery opens new possibilities for using mushrooms as biological factories to produce flavonoids for medical and nutritional applications.

Proteins from Edible Mushrooms: Nutritional Role and Contribution to Well-Being

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Mushrooms are highly nutritious foods containing proteins as complete and high-quality as meat, with unique compounds that boost immunity, fight infections, and may help prevent diseases like cancer and diabetes. Different types of mushroom proteins have specific health benefits, from strengthening immune systems to lowering blood pressure and fighting viruses. Scientists are finding new ways to grow mushrooms and extract their proteins for use in sports nutrition, medicines, and fortified foods, making them increasingly valuable for human health and sustainability.

Multiomics Provides a New Understanding of the Effect of Temperature Change on the Fermentation Quality of Ophiocordyceps sinensis

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This research studied how temperature affects the growth and quality of Ophiocordyceps sinensis, a valuable medicinal fungus. Scientists found that the fungus grows best between 18-23°C, and that temperatures above 28°C damage the fungus by triggering cell death processes. The study identified which genes and metabolites are affected by temperature changes, helping optimize large-scale production of this medicinal fungus.

Integrated multi-omics identifies plant hormone signal transduction and phenylpropanoid biosynthesis as key pathways in kiwifruit (Actinidia chinensis var. deliciosa) resistance to Botryosphaeria Dothidea infection

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Kiwifruit can be infected by a fungus called Botryosphaeria dothidea, which causes soft rot and makes the fruit inedible. Researchers used advanced techniques to study what happens inside the fruit when infected, finding that certain plant hormones and chemical pathways become active to fight the infection. They identified two key genes that appear to control how the fruit responds to the fungus, which could help develop better ways to prevent this costly disease.

Research Keyword: metabolomics