Research Keyword: membrane trafficking

Regulation of Oomycete Autophagy, Lipid Droplet Accumulation and Pathogenesis by Three Rab GTPases

This research investigates three protein molecules called Rab GTPases that control important cellular processes in a disease-causing organism called Peronophythora litchii, which damages litchi fruit crops. Scientists used modern gene-editing technology to remove these proteins and discovered they regulate how the pathogen grows, reproduces through spores, handles stress, and causes disease. The findings suggest these Rab proteins could be targeted to develop new strategies for controlling litchi downy blight and related plant diseases.

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Things you wanted to know about fungal extracellular vesicles (but were afraid to ask)

Fungal extracellular vesicles (EVs) are tiny packages released by fungal cells that play important roles in fungal infections and how our immune system responds to them. Scientists have confirmed these EVs are real biological structures, not laboratory artifacts, and discovered they are produced by many different fungal species. Interestingly, these EVs can have opposite effects on the immune system depending on the fungus involved—sometimes helping our bodies fight infection and sometimes making infections worse, making them both potential vaccines and virulence factors.

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