medicinal mushroom – Page 3

Haplotype-Phased Chromosome-Level Genome Assembly of Floccularia luteovirens Provides Insights into Its Taxonomy, Adaptive Evolution, and Biosynthetic Potential

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Scientists have created the most detailed genetic map of the yellow mushroom (Floccularia luteovirens), a highly valued medicinal and edible fungus from the Tibetan Plateau. Using advanced sequencing technology, they mapped its 13 chromosomes and identified 15 pathways that the mushroom uses to make potentially useful healing compounds. The research also solved a long-standing mystery about the mushroom’s family tree, proving it is not actually related to Armillaria mushrooms as previously thought. This genetic blueprint opens new possibilities for developing medicines from this special fungus.

Evidence-Based Nutraceuticals Derived from Antrodia cinnamomea

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Antrodia cinnamomea, a mushroom from Taiwan traditionally used for health, contains many beneficial compounds that fight inflammation, tumors, and oxidative stress. Research shows it can help with cancer, liver disease, diabetes, and high blood pressure. The mushroom can be grown in laboratories and its active compounds extracted using various modern techniques, making it promising for health supplements and medicines.

Genome Sequencing of Hericium coralloides by a Combination of PacBio RS II and Next-Generation Sequencing Platforms

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Scientists successfully sequenced the complete genome of Hericium coralloides, a medicinal mushroom used in traditional Chinese medicine for treating heart disease, cancer, and stomach problems. Using advanced sequencing technology combining long-read and short-read methods, they assembled the 55 million base pair genome containing over 11,700 genes. This genetic blueprint reveals the mushroom contains genes for producing beneficial enzymes and compounds with therapeutic potential. This milestone opens the door for future research to develop new medicines based on this mushroom’s natural bioactive properties.

Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

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Researchers studied how special fungal compounds called elicitors can boost the production of healing substances in a medicinal mushroom called Sanghuangporus sanghuang. By analyzing genes and metabolites, they found that adding elicitors increased beneficial compounds like betulinic acid and 2-hydroxyoleanolic acid by up to 114-fold. These findings suggest a practical way to produce more medicinal compounds from this mushroom for health applications.

Isolation and Antioxidant Mechanism of Polyphenols from Sanghuangporous vaninii

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Researchers found that a medicinal mushroom called Sanghuangporous vaninii grown on mulberry sawdust in China contains exceptionally high levels of polyphenols—powerful antioxidant compounds. They isolated and purified a particularly potent polyphenol mixture called HNMS3, which contains 33 different compounds. Through advanced molecular analysis, they discovered that HNMS3 works by activating eight key proteins in the body to fight oxidative stress, making it potentially beneficial for brain health and preventing nerve degeneration.

Comparative transcriptome analyses and CRISPR/Cas9-mediated functional study of Tfsdh1 reveal insights into the interaction between Tremella fuciformis and Annulohypoxylon stygium

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White wood ear fungus (Tremella fuciformis) is a popular medicinal mushroom that cannot grow on its own in nature. Researchers studied how it interacts with a companion fungus and discovered that a specific gene called Tfsdh1 is crucial for the mushroom to use sorbitol sugar and grow properly. By using advanced genetic tools to remove this gene, they showed it’s essential for the relationship between the two fungi, offering insights into how to better cultivate this nutritious mushroom.

A high-quality genome assembly of Lactarius hatsudake strain JH5

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Scientists have completed a detailed genetic blueprint of the red milk mushroom (Lactarius hatsudake), an edible and medicinal fungus that grows in pine forests. This mushroom is nutritious and has been shown to help with diabetes, boost immunity, and fight harmful bacteria. The new genetic map is much more complete and detailed than previous versions, which will help farmers grow these valuable mushrooms more reliably and sustainably, and could lead to developing better varieties.

Haplotype-resolved genomes of Phlebopus portentosus reveal nuclear differentiation, TE-mediated variation, and saprotrophic potential

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Researchers sequenced the complete genomes of two compatible versions of the black truffle fungus Phlebopus portentosus, the only Boletales species grown commercially. They discovered that jumping genes called transposable elements cause significant differences between the two fungal nuclei, affecting the production of beneficial compounds. The study shows this mushroom can both partner with tree roots and break down organic matter independently, making it versatile in nature and valuable for both food and medicine.

Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

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Scientists studied how a special fungal treatment can boost the production of beneficial compounds in sanghuang mushrooms. Using advanced molecular analysis techniques, they found that the fungal elicitor significantly increased levels of healing compounds called triterpenes. The treated mushrooms produced 114 times more of one specific compound compared to untreated mushrooms. This research shows how we can grow medicinal mushrooms with higher levels of beneficial substances, which could help develop better treatments for various diseases.

Construction of a genetic linkage map and detection of quantitative trait locus for the ergothioneine content in tamogitake mushroom (Pleurotus cornucopiae var. citrinopileatus)

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Researchers created the first genetic map of tamogitake mushrooms to identify genes controlling ergothioneine content. Ergothioneine is an antioxidant compound that provides health benefits like fighting inflammation and protecting brain health. They found one key genetic marker that reliably predicts which mushrooms will have high ergothioneine levels, enabling farmers to selectively breed mushrooms with enhanced health benefits.

Research Keyword: medicinal mushroom