medicinal fungus – mycolab.ai

A putative ABC transporter gene, CcT1, is involved in beauvericin synthesis, conidiation, and oxidative stress resistance in Cordyceps chanhua

mycolabadmin

Cordyceps chanhua is a medicinal fungus used in traditional Chinese medicine that produces a compound called beauvericin, which has health benefits but can be toxic in high amounts. Researchers discovered a gene called CcT1 that controls how much beauvericin the fungus makes. By removing this gene, they could reduce beauvericin production by 64%, making the fungus safer to use as medicine while maintaining other beneficial properties.

Domestication of a magic therapeutical wine glass fungus (Podoscypha petalodes) from Pakistan

mycolabadmin

Researchers successfully grew Podoscypha petalodes, a medicinal mushroom known as wine glass fungus, under controlled conditions for the first time. The best growth was achieved using a mixture of sawdust and tea waste at 28°C, which produced high yields in just 10 days. This breakthrough means that this therapeutic fungus, which has antiviral and anti-cancer properties, can now be cultivated year-round commercially instead of relying on rare wild specimens.

Metagenomic Analysis: Alterations of Soil Microbial Community and Function due to the Disturbance of Collecting Cordyceps sinensis

mycolabadmin

This research examines how harvesting Cordyceps sinensis (a valuable medicinal fungus) affects the soil’s microscopic organisms on the Tibetan Plateau. While collection doesn’t reduce the total number of microbes, it significantly changes which types live in the soil and how they function. The study found that collection alters important soil processes related to carbon, nitrogen, and phosphorus cycling, suggesting that harvesting practices need to balance economic benefits with environmental health.

Revitalization of the Endophytic Fungus Acremonium sp. MEP2000 and Its Impact on the Growth and Accumulation of Bioactive Compounds in Inonotus obliquus

mycolabadmin

Researchers successfully revived a beneficial fungus called Acremonium sp. MEP2000 that had lost its effectiveness through repeated cultivation by adding birch bark powder and medicinal mushroom powder to its growth medium. When used to treat the medicinal fungus Inonotus obliquus (chaga), this revitalized fungal culture dramatically improved the growth and production of healthy bioactive compounds like polysaccharides and triterpenoids. This breakthrough offers a practical solution for large-scale production of medicinal fungi with enhanced therapeutic potential for treating cancer, diabetes, and inflammatory conditions.

Transcriptomic insights into the molecular mechanism of abietic acid promoting growth and branching in Armillaria gallica

mycolabadmin

Scientists discovered that abietic acid, a natural compound from pine trees, significantly boosts the growth of Armillaria gallica mushrooms by up to 302% in just three days. This fungus is important because it helps grow Gastrodia elata, a valuable traditional Chinese medicinal herb. By studying which genes turned on in response to abietic acid, researchers found it works by helping the fungus break down nutrients more efficiently and remodel its cell walls for better growth. This discovery could improve cultivation techniques for medicinal mushrooms and their plant partners.

Whole-Genome Sequencing and Comparative Genomics Analysis of the Wild Edible Mushroom (Gomphus purpuraceus) Provide Insights into Its Potential Food Application and Artificial Domestication

mycolabadmin

Scientists sequenced the complete genetic code of Gomphus purpuraceus, a wild mushroom eaten in southwest China for hundreds of years. By comparing its genes to other edible mushrooms, researchers discovered it likely forms beneficial partnerships with trees and can break down some plant material. The study shows this mushroom can efficiently use simple sugars like sucrose and maltose for growth, which could help farmers grow it commercially while preserving this rare species.

Evidence-Based Nutraceuticals Derived from Antrodia cinnamomea

mycolabadmin

Antrodia cinnamomea, a mushroom from Taiwan traditionally used for health, contains many beneficial compounds that fight inflammation, tumors, and oxidative stress. Research shows it can help with cancer, liver disease, diabetes, and high blood pressure. The mushroom can be grown in laboratories and its active compounds extracted using various modern techniques, making it promising for health supplements and medicines.

Pan-genomic characterization and structural variant analysis reveal insights into spore development and species diversity in Ganoderma

mycolabadmin

Researchers completed the first comprehensive genome study of 15 Ganoderma (Lingzhi/Reishi) varieties, including five new Chinese strains. They discovered that specific genetic changes in the MSH4 gene dramatically increase spore production in one superior strain. These findings help explain why different Ganoderma varieties have different medicinal properties and can guide breeding of better medicinal mushroom varieties.

Research Keyword: medicinal fungus