Medicinal fungi – Page 2

Comparative transcriptome analysis reveals the role of sugar signaling in response to high temperature stress in Armillaria gallica

mycolabadmin

Scientists studied how a fungus called Armillaria gallica responds to high heat, which is important because this fungus forms a partnership with a valuable medicinal plant called Gastrodia elata. They compared a heat-tolerant fungal strain with a heat-sensitive one and found that the heat-tolerant strain increases sugar accumulation and activates specific genes that help it survive hot conditions. Adding sucrose to the fungus’s growth medium helped it tolerate heat better, suggesting that sugar plays a key role in heat stress protection.

Fusarium pseudonygamai Promotes Blastospore Transformation in Ophiocordyceps sinensis: Insights into Microbial Interaction and Key Mechanisms

mycolabadmin

This study reveals how a beneficial microorganism (Fusarium pseudonygamai) helps the medicinal fungus Chinese cordyceps transform and grow properly. The microorganism produces a natural sugar-like substance called mannitol that signals the fungus to change from spore form into thread-like hyphae. By understanding this microbial communication, scientists can potentially improve the artificial production of Chinese cordyceps, reducing pressure on wild populations.

Selection and validation of reference genes for RT-qPCR in ophiocordyceps sinensis under different experimental conditions

mycolabadmin

Scientists studied the Chinese caterpillar mushroom (Ophiocordyceps sinensis) to find the best genes to use as reference points when measuring other gene activity. They tested sixteen potential reference genes under various stress conditions and growth stages using a technique called RT-qPCR. They found that two specific genes (18S rRNA and beta-Tubulin) were the most reliable to use as standards, which will help researchers accurately study how this medicinal mushroom responds to different conditions.

Biological Characteristics and Domestication of Dichomitus squalens and the Antioxidant Activity of Its Cultivated Fruiting Bodies

mycolabadmin

Researchers cultivated a type of fungus called Dichomitus squalens and extracted beneficial compounds called polysaccharides from its fruiting bodies. These polysaccharides showed strong antioxidant properties, meaning they can help protect cells from damage caused by harmful free radicals. The study identified the best growing conditions for this fungus and developed methods for farming it, suggesting it could become a natural source of antioxidants for health applications.

Updated Taxonomy of Chinese Craterellus (Hydnaceae, Cantharellales) with Three New Species Described

mycolabadmin

Scientists have discovered and described three new species of trumpet mushrooms (Craterellus) found in China. These mushrooms are valuable because they form helpful relationships with trees and have medicinal properties. By studying both the physical characteristics and DNA of 109 mushroom samples, researchers identified seventeen different Craterellus species in China, greatly expanding our understanding of this important group of edible fungi.

From Mushrooms to Molecules: Exploring Depsidones in Ganoderma lucidum for Antioxidant and Anticancer Applications

mycolabadmin

This research examined reishi mushroom (Ganoderma lucidum), a traditional medicinal fungus, to find rare compounds called depsidones with potential cancer-fighting properties. Scientists extracted these compounds using different solvents and tested them against four types of cancer cells (liver, colon, breast, and lung cancer), finding that they successfully killed cancer cells while being safe to normal cells. Using advanced chemical analysis and computer modeling, they identified nine new depsidone compounds in reishi and showed how these compounds could bind to cancer-related proteins to stop tumor growth.

Insights into the Mycosphere Fungal Community and Its Association with Nucleoside Accumulation in Ophiocordyceps sinensis

mycolabadmin

Chinese cordyceps (Ophiocordyceps sinensis) is a precious medicinal fungus found on the Tibetan Plateau that has anti-inflammatory and anti-tumor properties. Researchers studied the fungi living in soil around wild cordyceps and found that the types and amounts of these soil fungi are connected to how much medicinal compounds accumulate in the cordyceps. Samples from certain regions like Yushu had more diverse soil fungi and higher levels of beneficial compounds called nucleosides. This suggests that managing soil fungi could help improve the quality of cordyceps grown in cultivation.

Biological Characteristics, Artificial Domestication Conditions Optimization, and Bioactive Components of Beauveria caledonica

mycolabadmin

Scientists successfully grew Beauveria caledonica mushrooms in a laboratory for the first time using wheat and rice as growing media. They identified the best growing conditions and found that these mushrooms contain beneficial compounds like polysaccharides and adenosine, which may have health benefits similar to traditional medicinal Cordyceps. The adenosine content was significantly higher than what is required by Chinese pharmacopoeia standards, suggesting these cultivated mushrooms could have strong medicinal value.

Insights into microbiome-triterpenoid correlation in Poria cocos via comparative analysis of sclerotial and soil microenvironments

mycolabadmin

This study explores how the medicinal mushroom Poria cocos creates its own special microbial environment inside its sclerotium (the part used in medicine). Researchers found that the mushroom selectively enriches certain bacteria and fungi while maintaining lower overall microbial diversity compared to surrounding soil. The study reveals that specific microbes like Burkholderia and Scytalidium are positively associated with the production of pachymic acid, the mushroom’s key medicinal compound with anti-tumor and anti-inflammatory properties.

Whole genome sequencing and annotations of Trametes sanguinea ZHSJ

mycolabadmin

Scientists sequenced the complete genome of Trametes sanguinea, a medicinal mushroom used in traditional Chinese medicine, grown in China. The mushroom’s tissue contains beneficial compounds that may help fight tumors, protect the heart, boost immunity, and heal diabetic wounds. By mapping out all 10,886 genes in this fungus, researchers now have detailed blueprints to understand how it produces these healing compounds and potentially grow them industrially for medical use.

Research Keyword: Medicinal fungi