Research Keyword: medical mycology

Humans vs. Fungi: An Overview of Fungal Pathogens against Humans

Fungal infections are serious health threats that kill approximately 1.5 million people annually worldwide. This comprehensive review identifies over 280 different fungal species that can infect humans, with Aspergillus being the most dangerous genus. The study provides updated information on how these infections are diagnosed through various methods including cultures, microscopy, and molecular testing, as well as treatment options ranging from traditional antifungal drugs to newer therapies like nanotechnology-based formulations.

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Advances in Fungal Infection Research: From Novel Diagnostics to Innovative Therapeutics

Fungal infections are becoming increasingly serious, especially for people with weakened immune systems, and some fungi are developing resistance to current medications. Researchers are developing faster diagnostic tests using molecular techniques and exploring new treatment approaches including repurposing existing drugs and developing vaccines. Monitoring and prevention programs in hospitals are essential to control the spread of these infections and improve patient outcomes.

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Medical Mycology Education in Brazil: A Cross-Sectional Survey of Medical Schools

This study examined how medical schools in southern Brazil teach students about fungal infections. The researchers surveyed 19 medical schools and found that while all schools include some mycology teaching, it is not offered as a standalone course and there are significant gaps in practical training, laboratory facilities, and instructor expertise. The study highlights that despite Brazil’s burden of serious fungal infections, future doctors are often not adequately prepared to recognize and manage these diseases.

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MycoNews 2023: Editorial, news, reports, awards, personalia, and book news

This report highlights major developments in mycology during 2023, featuring updates from international fungal research conferences held around the world. It covers new awards recognizing fungal research including innovative uses of fungi for environmental cleanup and sustainable energy storage. The report also discusses emerging therapeutic uses of psilocybin-containing mushrooms for treating depression and anxiety, and emphasizes the importance of international gatherings for mycologists to share discoveries and collaborate.

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Advancing Patient Advocacy in Mycology: Cultivating Collaboration in Education, Research, and Policy

This paper highlights how patients with fungal infections and their caregivers are rarely included in discussions about healthcare policies and research funding, unlike patients with cancer or HIV. The authors argue that fungal diseases deserve more attention and resources, and that listening to patient experiences is essential for improving how these diseases are prevented, diagnosed, and treated. They propose that dedicated advocacy organizations, like the MyCARE Foundation, can help bridge this gap and ensure fungal infections receive the policy support and research investment they need.

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Drug repurposing to fight resistant fungal species: Recent developments as novel therapeutic strategies

Fungal infections are becoming increasingly difficult to treat due to growing drug resistance, affecting millions of people worldwide each year. This research collection explores creative solutions by repurposing existing medications and developing new combination therapies that work better together against resistant fungal species. Studies show promising results combining common antibiotics like minocycline with antifungal drugs, and natural compounds from traditional medicine show potential for treating hard-to-treat infections like Candida and Aspergillus.

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Molecular Identification of Candida Species among Iranian Patients: Pursuing Candida auris

This study evaluated a simple molecular test called PCR-RFLP to identify different types of Candida fungi in hospitalized patients in Iran. Among 136 patient samples, researchers found eight different Candida species, with common Candida albicans being most prevalent, but other more dangerous species also present. No cases of the emerging pathogen Candida auris were found, though the test method can effectively detect it. The researchers conclude this cost-effective test could be valuable for identifying dangerous fungal infections in developing countries.

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The Impact of the Fungal Priority Pathogens List on Medical Mycology: A Northern European Perspective

Fungal infections affect over a billion people worldwide but are often overlooked in healthcare. The World Health Organization recently created a priority list of dangerous fungi to help doctors and researchers focus their efforts. This review discusses how this list can improve diagnosis, testing, and treatment of fungal infections across Europe, while also highlighting the need for better training and awareness among healthcare workers.

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Strengthening Fungal Infection Diagnosis and Treatment: An In-depth Analysis of Capabilities in Honduras

This study examined how well healthcare facilities in Honduras can diagnose and treat serious fungal infections. Researchers surveyed laboratories and hospitals to find out what diagnostic tools and antifungal medications were available. The findings showed that while basic tests like microscopy were common, advanced techniques were rare, and many important antifungal drugs were difficult to access. The study recommends improving training, building better laboratories, and making essential medications more available.

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Evaluation of Clinical, Microbiological Profiles and Management Patterns with Outcomes of Patients with Fungal Isolates in An Intensive Care Unit of A Tertiary Care Center: A Prospective Observational Study

This study examined fungal infections in patients staying in intensive care units at a hospital. Researchers found that diabetes was the most common risk factor, and a fungus called Candida tropicalis was the most frequently isolated organism from urine samples. Many of the fungal strains were resistant to fluconazole, a common antifungal medication, suggesting doctors need to choose different treatments based on which drugs the fungi are resistant to.

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