Sandalwood Sesquiterpene (Z)-α-Santalol Exhibits In Vivo Efficacy Against Madurella mycetomatis in Galleria mellonella Larvae
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Researchers tested sandalwood compounds against a fungal infection that causes a tropical disease called eumycetoma. Using a laboratory model with wax moth larvae infected with the fungus, they found that a specific compound called (Z)-α-santalol significantly extended the survival of infected larvae. This compound was more effective than current antifungal drugs and showed promise as a potential new treatment for this neglected tropical disease.