Research Keyword: MCF-7 cells

Synthesis of fungal polysaccharide-based nanoemulsions for cancer treatment

Researchers developed tiny capsules (nanoemulsions) made from corn protein and chitosan to better deliver shiitake mushroom compounds to treat cancer and reduce inflammation. When shiitake extract was enclosed in these nano-sized carriers, it became much more effective at killing breast cancer cells, fighting bacteria, and reducing inflammation compared to using the mushroom extract alone. This technology could lead to new natural medicines and health supplements that are more effective at lower doses.

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Evaluation of Anticancer Potential of Ganoderma lucidum on MCF-7 Breast Cancer Cells Through Genetic Transcription of Energy Metabolism

Researchers tested extracts from Ganoderma lucidum (Reishi mushroom) against breast cancer cells in the laboratory. They found that the methanol extract was particularly effective at killing cancer cells while leaving healthy cells relatively unharmed. The mushroom works by disrupting the cancer cells’ metabolism and triggering programmed cell death, making it a promising natural treatment option that could complement conventional cancer therapies.

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Taxonomic characterization and cytotoxic potential of Vietnamese Ganoderma ellipsoideum against human breast cancer MCF-7 cells

Scientists discovered a mushroom species called Ganoderma ellipsoideum in Vietnam that shows promise in fighting breast cancer. When tested on cancer cells in the laboratory, extracts from this mushroom killed cancer cells effectively. Computer modeling showed that compounds from this mushroom fit perfectly into and block proteins that help cancer cells grow and spread. This discovery suggests the mushroom could be a natural source for developing new cancer drugs.

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Phallus indusiatus Extracts Promoted MCF-7 Apoptosis Under TNFα-induced Tumor Microenvironment by Attenuating NF-kappaB and Akt Activation

Bamboo mushroom extracts show promise in helping treat breast cancer by making cancer cells more sensitive to chemotherapy drugs. The mushroom reduces inflammation and blocks protective signals in cancer cells, making them more likely to die. This research suggests bamboo mushroom could be a helpful supplement for breast cancer patients, especially when used alongside standard cancer treatments.

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Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

Two species of medicinal fungi were studied to understand why one was better at fighting cancer cells. Researchers analyzed the chemicals, genes, and proteins in both fungi and found that Phylloporia crataegi had much higher levels of cancer-fighting compounds and activated special cellular defense pathways that harm cancer cells. This research shows that medicinal fungi could be promising sources for developing new cancer treatments.

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