Research Keyword: Matrix metalloproteinases

Antimicrobial and prebiotic properties of Weissella confusa B4-2 exopolysaccharide and its effects on matrix metalloproteinase genes expression

Researchers discovered that a bacterium called Weissella confusa produces a sticky substance (exopolysaccharide) that has multiple health benefits. This substance fights harmful bacteria, acts as an antioxidant, helps heal wounds, and may slow down skin aging by reducing proteins that break down collagen. Because this bacterium produces much more of this substance than other commonly studied bacteria, it could be used in food preservation, health supplements, and anti-aging skincare products.

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Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity

Scientists discovered that a protein called TIMP2, which is naturally higher in young blood, plays a crucial role in maintaining brain memory and learning ability. Using laboratory mice, they found that TIMP2 helps keep the brain’s cellular environment flexible by controlling the buildup of structural proteins around nerve connections. Without adequate TIMP2, the brain develops more rigid connections that interfere with forming new memories and creating new brain cells, mimicking changes seen in aging and cognitive decline.

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Mycochemistry, antioxidant activity and anticancer potentiality of ethyl acetate extract of Daldinia eschscholtzii against A549 lung cancer cell line

Researchers studied a wild fungus called Daldinia eschscholtzii to see if it could fight lung cancer. They found that an extract from this fungus contained 28 different beneficial compounds and was effective at killing cancer cells by triggering a process called apoptosis (programmed cell death). The treatment also reduced the cancer cells’ ability to spread, and it appeared safe for normal, healthy cells. Several compounds in the extract showed promise as potential anti-cancer drugs.

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High Efficiency In Vitro Wound Healing of Dictyophora indusiata Extracts via Anti-Inflammatory and Collagen Stimulating (MMP-2 Inhibition) Mechanisms

This study examines bamboo mushroom extracts for their ability to promote skin wound healing. Researchers tested three different parts of immature bamboo mushrooms and found that the core extract was particularly effective at reducing inflammation and preventing excessive collagen breakdown, which helps wounds heal properly without excessive scarring. The extract performed as well as or better than standard pharmaceutical agents, suggesting it could be a promising natural ingredient for wound healing products.

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Skin Improvement with Antioxidant Effect of Yuja (Citrus junos) Peel Fractions: Wrinkles, Moisturizing, and Whitening

Yuja, a citrus fruit traditionally used in Asian medicine, shows promising benefits for skin health. This study found that extracts from Yuja peels can help reduce wrinkles, improve skin moisture, and lighten dark spots by protecting skin cells from UV damage and reducing harmful free radicals. The effects work through natural mechanisms that boost collagen production and inhibit melanin overproduction, making Yuja peel fractions promising ingredients for new skincare products.

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Exploring the Anticancer Potential of Coriolus versicolor in Breast Cancer: A Review

Coriolus versicolor, also known as turkey tail mushroom, has been used in traditional Chinese medicine for thousands of years. Recent scientific research shows it may help fight breast cancer through multiple mechanisms: killing cancer cells directly through programmed cell death pathways, breaking down the estrogen that fuels some breast cancers, preventing cancer spread, and boosting the immune system. While early studies are promising and one clinical trial showed good safety and immune benefits, larger studies are needed before this mushroom can be recommended as an official cancer treatment.

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