Research Keyword: MALDI-TOF MS identification

Trichosporon species bloodstream infections in a tertiary care hospital in the western region of Saudi Arabia: A 7-year retrospective chart review from 2016 to 2022

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This study examined a rare but dangerous fungal infection called Trichosporonosis that affects the bloodstream in hospitalized patients. Researchers found that this infection kills about 60% of patients despite treatment with antifungal medications. The infection is often caused by a fungus called Trichosporon asahii and typically occurs in patients with weakened immune systems who are already hospitalized and using catheters.

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First report of infections due to Candidozyma (formerly Candida) auris in Botswana, 2022–2024

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Researchers in Botswana discovered the first documented cases of a dangerous fungal infection called Candidozyma auris in their country. This yeast was found in 10 patients at a major hospital, mostly in intensive care units, between 2022 and 2024. The fungus was resistant to common antifungal drugs like fluconazole but could still be treated with other medications. The findings highlight how this emerging pathogen is spreading across Africa and stress the importance of improved laboratory testing and disease monitoring in developing countries.

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Rhino-orbital-cerebral mucormycosis in diabetic ketoacidosis: A classic clinical presentation still unknown in Senegal

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A young woman in Senegal with uncontrolled diabetes developed a serious fungal infection affecting her eye and brain caused by Rhizopus oryzae. Despite showing classic warning signs like swelling and tissue death, the infection was not diagnosed quickly enough, and the necessary antifungal medication (amphotericin B) was not available, resulting in her death within three days. This case highlights how invasive fungal infections are underrecognized and undertreated in Africa due to limited laboratory capacity and drug availability.

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