Research Keyword: liver transplantation

Clinical significance and outcomes of adult living donor liver transplantation for acute liver failure: a retrospective cohort study based on 15-year single-center experience

mycolabadmin

Researchers studied 267 patients with acute liver failure over 15 years to compare two types of liver transplants: using living donors versus deceased donors. Living donor transplants worked just as well as deceased donor transplants, with similar patient survival rates, but allowed faster surgery before patients became critically ill. When a suitable living donor was available, performing the transplant quickly before severe brain complications developed led to better patient outcomes.

Read More »

Acute liver failure caused by Amanita verna: a case series and review of the literature

mycolabadmin

This case study examines three patients who became severely ill after eating poisonous Amanita verna mushrooms in China. One patient successfully received a liver transplant and recovered, while the other two died from brain bleeding complications. The study highlights that liver transplantation can be life-saving for mushroom poisoning victims with severe liver failure, though doctors need better guidelines to decide when transplantation is the right choice.

Read More »

Educational Case: Acetaminophen hepatotoxicity: Pathophysiology and evaluation of acute liver failure

mycolabadmin

This educational case describes how acetaminophen overdose causes severe liver damage leading to acute liver failure. The toxic form of acetaminophen damages liver cell mitochondria and causes widespread cell death, particularly in the center of liver lobules. Treatment with N-acetylcysteine within 24 hours of overdose significantly improves outcomes, though severe cases require liver transplantation.

Read More »
Scroll to Top