Research Keyword: LD50

A human-relevant alternative infection model for mucormycosis using the silkworm Bombyx mori

Researchers developed a silkworm-based model to study mucormycosis, a deadly fungal infection. The model reproduces the same disease patterns and risk factors seen in humans, including effects of steroids and iron levels. Importantly, it successfully predicted how well antifungal drugs work against the infection, offering a faster and more ethical alternative to mammal testing for developing new treatments.

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