Research Keyword: LC-MS/MS

The Major Stilbene Compound Accumulated in the Roots of a Resistant Variety of Phoenix dactylifera L. Activates Proteasome for a Path in Anti-Aging Strategy

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Researchers found that date palm roots from disease-resistant varieties contain a special compound called 3,3′,4,5,5′-pentahydroxy-trans-stilbene that acts as a natural antioxidant and anti-aging agent. This compound can protect aging skin cells by activating the proteasome, which is like the cell’s recycling system that removes damaged proteins. The findings suggest this natural compound could potentially help slow down skin aging and protect against age-related diseases.

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Integrated Transcriptomic and Proteomic Analyses Reveal Molecular Mechanism of Response to Heat Shock in Morchella sextelata

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Morels are delicious mushrooms that are difficult to grow because they are very sensitive to high temperatures. Scientists compared two different morel strains to understand why one variety can tolerate heat better than the other. By studying the genes and proteins expressed at normal and high temperatures, researchers discovered that the heat-tolerant strain activates specific protective mechanisms, particularly through a protein called Rsp5 that helps boost other protective proteins. This research provides valuable information for breeding morel varieties that can survive warmer growing conditions in the age of climate change.

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Unveiling the Substrate-Dependent Dynamics of Mycotoxin Production in Fusarium verticillioides Using an OSMAC-Metabolomics Approach

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Researchers studied how different growing conditions affect the production of harmful toxins by a fungus called Fusarium verticillioides that contaminates crops. Using advanced chemical analysis techniques, they found that the type of growth medium and time of incubation significantly influenced which toxins the fungus produced and in what amounts. Growing the fungus on corn-based medium produced different toxins than growing it on barley-based medium. These findings can help develop better strategies to prevent mycotoxin contamination in food and animal feed.

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Metabolomics analysis of mycelial exudates provides insights into fungal antagonists of Armillaria

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This study examined how two types of honey mushrooms (Armillaria) fight each other when grown together. Researchers found specific chemical markers and metabolic pathways that are activated during this competition. The study identified 156 new compounds produced during co-culture, including 32 with potential antifungal properties. These findings could help understand how mushrooms naturally combat fungal pathogens.

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