Research Keyword: kojic acid production

The Zn(II)2-Cys6-type zinc finger protein AoKap7 is involved in the growth, oxidative stress and kojic acid synthesis in Aspergillus oryzae

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Scientists studied a protein called AoKap7 in a fungus (Aspergillus oryzae) that produces kojic acid, a substance used in cosmetics and medicine. When they removed this protein, the fungus grew faster but made less kojic acid and became more vulnerable to stress. The researchers found that AoKap7 controls several genes that help the fungus protect itself from harmful molecules and produce kojic acid efficiently.

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Aokap9 gene knockout contributes to kojic acid synthesis in Aspergillus oryzae

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Researchers discovered that removing the Aokap9 gene in the fungus Aspergillus oryzae doubles the production of kojic acid, a valuable chemical used in skin-whitening cosmetics and food preservation. By combining the Aokap9 gene removal with modifications to other genes (kojR and AozfA), they achieved even higher production levels. This research provides a practical pathway for creating high-yield strains that can produce kojic acid more efficiently for commercial applications.

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The Zn(II)2-Cys6-type zinc finger protein AoKap7 is involved in the growth, oxidative stress and kojic acid synthesis in Aspergillus oryzae

mycolabadmin

Researchers studied a protein called AoKap7 in a fungus used to produce kojic acid, which is found in many cosmetic and food products. By deleting this protein gene, they found that fungi grew faster but produced much less kojic acid and were more sensitive to stress. The protein works as a master switch that controls both how fast the fungus grows and how much of the valuable kojic acid it makes.

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