Research Keyword: ITS1 sequencing

Mycobiome analyses of critically ill COVID-19 patients

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This study examined fungal infections in severely ill COVID-19 patients treated in intensive care units across Europe. Researchers found that a dangerous mold called Aspergillus fumigatus was more common in patients who died and less common in those treated with azole antifungal drugs. The findings suggest that giving antifungal medications to critically ill COVID-19 patients when they arrive at the hospital might help prevent fungal-related deaths.

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Insights into microbiome-triterpenoid correlation in Poria cocos via comparative analysis of sclerotial and soil microenvironments

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This study explores how the medicinal mushroom Poria cocos creates its own special microbial environment inside its sclerotium (the part used in medicine). Researchers found that the mushroom selectively enriches certain bacteria and fungi while maintaining lower overall microbial diversity compared to surrounding soil. The study reveals that specific microbes like Burkholderia and Scytalidium are positively associated with the production of pachymic acid, the mushroom’s key medicinal compound with anti-tumor and anti-inflammatory properties.

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Characterization of fungal communities transmitted from sow to piglet

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This study examined how fungi from mother pigs are passed to their newborn piglets. Researchers collected samples from sow feces, sow vaginas, and piglet feces and analyzed the fungal communities using genetic sequencing. They found that about 47% of the fungi in piglet feces came from the mother’s intestines, while a small amount came from the vagina, with the remainder from unknown environmental sources. The findings help us understand how maternal fungi help establish a healthy gut in newborns.

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