Research Keyword: ITS gene sequencing

Detection and diagnostic process of liver abscess secondary to chemotherapy by mucor indicus in a patient with acute leukemic disease: case report

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A 60-year-old man with acute leukemia developed a serious fungal infection in his liver caused by Mucor indicus after receiving chemotherapy that weakened his immune system. Doctors identified the infection through tissue samples and genetic testing, then treated him successfully with antifungal medications amphotericin B and posaconazole. This case highlights the importance of early detection and proper diagnosis of rare fungal infections in cancer patients undergoing chemotherapy.

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Identification and growth-promoting effect of Paecilomyces lilacinus a biocontrol fungi for walnut rot disease

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Scientists identified a beneficial fungus called Paecilomyces lilacinus from walnut soil that can fight walnut rot disease more safely than chemical fungicides. Testing showed this fungus not only kills the disease-causing pathogen but also boosts walnut seed germination and seedling growth by up to 98%. This natural solution could help walnut farmers protect their crops while avoiding harmful chemical pesticides.

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Schizophyllum commune infection following chimeric antigen receptor T-cell therapy in a patient with lymphoma

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A 71-year-old woman receiving CAR T-cell therapy for lymphoma developed a rare fungal lung infection caused by Schizophyllum commune six months after treatment. The infection presented similarly to other fungal diseases affecting the lungs and was diagnosed through bronchoscopy and fungal culture despite negative blood antibody tests. Standard antifungal medication (voriconazole) taken by mouth for four months completely resolved the infection, highlighting the need to consider rare fungi in patients receiving advanced cancer immunotherapies.

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Saksenaea oblongispora Rhinosinusitis in Advanced HIV: A Rare and Lethal Mucormycosis

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A 32-year-old man with advanced HIV developed a severe fungal infection of his sinuses caused by a rare fungus called Saksenaea oblongispora, which typically doesn’t affect people with HIV. The patient presented with severe facial swelling that rapidly worsened, and despite doctors identifying the fungus through biopsies and lab tests, he did not receive antifungal treatment or surgery before his condition became critical. This is the first case of this particular fungal infection documented in sub-Saharan Africa and in HIV patients, highlighting how dangerous this rare infection can be and how challenging it is to diagnose quickly enough to save lives.

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Screening of yeasts in the oral microbiota of bats (Chiroptera) in Piauí, Brazil

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Researchers collected oral samples from 47 bats in Brazil and found that over 40% carried yeast species, including some dangerous types like Candida albicans that cause infections in humans. The study identified that bats living near human settlements may serve as reservoirs for these disease-causing fungi, especially during rainy seasons when conditions favor yeast growth. This discovery highlights the importance of monitoring wildlife for infectious diseases to prevent them from spreading to humans.

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Identification of novel polyethylene-degrading fungi from South African landfill soils: Arthrographis kalrae, Lecanicillium coprophilum, and Didymosphaeria variabile

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Researchers in South Africa discovered three new types of fungi that can break down plastic waste in landfills. These fungi, along with two previously known species, were found in soil from two landfill sites and were shown to degrade polyethylene plastic. The scientists used multiple testing methods to confirm the fungi actually decompose the plastic by breaking down its chemical structure. This discovery offers hope for a biological solution to South Africa’s serious plastic waste problem.

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Identification and growth-promoting effect of Paecilomyces lilacinus a biocontrol fungi for walnut rot disease

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Researchers identified a beneficial fungus called Paecilomyces lilacinus that can fight walnut rot disease, which damages walnut crops especially in China’s Xinjiang region. This fungus is more environmentally friendly than chemical fungicides and actually boosts walnut plant growth, increasing seedling height and root development significantly. The study shows it could replace harmful chemical treatments while improving overall plant health.

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