Research Keyword: isothermal amplification

Development of reverse transcription loop-mediated isothermal amplification-based assay for rapid and specific detection of human fungal pathogen, Candida auris

Researchers developed a new rapid test called RT-LAMP to detect Candida auris, a dangerous multidrug-resistant fungus that causes hospital infections. The test works by changing color from pink to yellow when the fungus is present, making it easy to read without special equipment. It is more sensitive and specific than current methods, can be done quickly at a single temperature, and costs much less than existing tests, making it ideal for hospitals and clinics with limited resources.

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Simultaneous Detection of Four Madurella Species Using Loop-Mediated Isothermal Amplification (LAMP) for Eumycetoma Diagnosis

Scientists developed a simple new test to identify four types of fungi that cause a serious tropical disease called eumycetoma. Unlike previous tests that required expensive equipment and multiple reactions, this new test works in one tube using simple heating instead of complex thermal cycling. The test can detect the fungi in about 45 minutes and works reliably in remote areas with limited resources.

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