Research Keyword: interneurons

Erythropoietin restrains the inhibitory potential of interneurons in the mouse hippocampus

Researchers studied how a protein called erythropoietin (EPO) affects brain cells called interneurons in the hippocampus, a region important for memory and learning. They found that EPO treatment reduces the inhibitory activity of certain interneurons, which makes the brain’s excitatory neurons more active. This change in brain balance could potentially help treat psychiatric disorders like schizophrenia and autism that involve imbalanced brain activity.

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Hierarchical communities in the larval Drosophila connectome: Links to cellular annotations and network topology

Scientists studying fruit fly larval brains discovered that neurons are organized into nested groups or communities, much like departments within a company. These communities perfectly match what scientists knew about neuron types and their functions. Remarkably, certain interneurons act as hubs connecting these different communities, allowing information to flow between specialized brain regions. This organization reveals that the brain’s wiring reflects both its structure and its function.

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