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Molecular identification of yeast communities isolated from nail specimens by PCR-RFLP and PCR-FSP methods

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This study developed and compared two molecular methods to accurately identify different yeast species that cause nail infections. Researchers tested 269 patient samples and found that both PCR-RFLP and PCR-FSP methods were effective, with PCR-FSP being better at identifying rare yeast species. These methods help doctors identify the exact type of yeast causing infection, which is important for selecting the right antifungal medication for treatment.

Prevalence and antifungal susceptibility profiles of Candida isolates among patients with candiduria: a multiplex PCR assay

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Researchers studied urinary tract infections caused by yeast (Candida species) in hospitalized patients. Using advanced molecular testing, they found that while the common yeast Candida albicans was most prevalent, other yeast species were increasingly showing resistance to antifungal medications, particularly to fluconazole. The study highlights the importance of identifying which specific yeast species is causing an infection to choose the most effective treatment.

Madurella tropicana and Madurella pseudomycetomatis identified as new causative agents of black grain eumycetoma in Senegal

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This case report describes two patients in Senegal with a serious fungal infection called eumycetoma caused by previously unidentified fungal species. Using modern DNA sequencing methods, researchers identified the infections as being caused by Madurella tropicana and Madurella pseudomycetomatis, rather than the previously known Madurella mycetomatis. One patient treated with the antifungal drug itraconazole showed good improvement, highlighting the importance of accurate identification for proper treatment.

Four Unrecorded Species of Endophytic Diaporthe (Sordariomycetes) in Korea

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Researchers in Korea discovered four types of fungi living inside plants without causing harm, called endophytic fungi. These fungi belong to a genus called Diaporthe and were identified using DNA analysis and microscopic examination. The study helps us understand the hidden diversity of fungi living in Korean plants and could lead to discovering new medicines or ways to control plant diseases.

Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in Thailand

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Researchers in Thailand have identified five patients with a difficult-to-treat fungal skin infection caused by Trichophyton indotineae, a type of dermatophyte that resists the commonly used antifungal drug terbinafine. This is the first time this resistant fungus has been detected in Thailand. The team developed a simple, inexpensive test using urease to help identify these resistant infections more easily. Patients responded well to the antifungal drug itraconazole after other treatments failed.

Molecular Identification of Candida Species among Iranian Patients: Pursuing Candida auris

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This study evaluated a simple molecular test called PCR-RFLP to identify different types of Candida fungi in hospitalized patients in Iran. Among 136 patient samples, researchers found eight different Candida species, with common Candida albicans being most prevalent, but other more dangerous species also present. No cases of the emerging pathogen Candida auris were found, though the test method can effectively detect it. The researchers conclude this cost-effective test could be valuable for identifying dangerous fungal infections in developing countries.

Identification of fungal agents isolated from burn lesions using mycological and molecular methods in patients admitted to Velayat burn hospital in Rasht city during 2022–2023

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Researchers studied fungal infections in burn patients at a hospital in Iran and found that non-albicans Candida fungi, particularly a species called Candida parapsilosis, were the most common culprits. Using laboratory cultures and genetic testing, they identified 101 fungal infections out of 380 burn patients. Understanding which fungi cause these infections is important for doctors to choose the right treatment and improve patient outcomes.

Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in Thailand

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Researchers in Thailand identified five patients with a new type of fungal skin infection caused by Trichophyton indotineae, a species that resists the common antifungal drug terbinafine. These infections appeared as rashes on various parts of the body and required treatment with alternative medications like itraconazole. The findings represent the first confirmed cases in Thailand and suggest this resistant fungus may be spreading globally. The study also showed that a simple urease test could help doctors identify this resistant strain quickly without waiting for complex genetic testing.

Spread of Antifungal-Resistant Trichophyton indotineae, United Kingdom, 2017–2024

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A dangerous fungal infection called Trichophyton indotineae is rapidly spreading across the United Kingdom, particularly among people with connections to South Asia. This infection causes stubborn skin rashes that don’t respond well to common antifungal treatments like terbinafine. The number of cases has skyrocketed, making up 38% of all dermatophyte infections by 2024, and doctors need to be aware of this emerging threat.

Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in Thailand

mycolabadmin

Doctors in Thailand have identified a new drug-resistant fungal infection caused by Trichophyton indotineae, a fungus that doesn’t respond to common antifungal medication terbinafine. Five patients were diagnosed with this resistant skin infection that caused rashes on various body parts and failed to improve with standard treatments. The research shows that a simple urease test can help doctors quickly identify this resistant fungus, and a different drug called itraconazole appears to work better for treatment. This is the first time this resistant fungus has been confirmed in Thailand, suggesting it is spreading globally.

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