Research Keyword: inflammatory response

Regulatory effects of Lycium Barbarum polysaccharides on immune function and their application prospects

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Lycium barbarum, a plant used in traditional Chinese medicine for over 2000 years, contains special compounds called polysaccharides that boost the immune system. These compounds work by activating immune cells like macrophages and T cells, and can help fight infections and reduce inflammation. Research shows they may also help with conditions like arthritis, cancer, and gut health by acting as a natural prebiotic that promotes beneficial bacteria.

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Lentinan Alleviated PM2.5 Exposure-Induced Epithelial–Mesenchymal Transition in Pulmonary Epithelial Cells by Inhibiting the GARP/TGF-β/Smad Pathway

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Air pollution particles (PM2.5) can cause serious lung damage by triggering a process called epithelial-mesenchymal transition, where lung cells lose their protective qualities. This study found that a natural compound called lentinan, derived from shiitake mushrooms, can help prevent this harmful process by blocking a protein called GARP. The research suggests that lentinan could be a promising natural treatment for lung diseases caused by air pollution.

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Winning the battle of intestinal peace with Bacillus—a multifaceted approach to animal health, immunity, and future applications in monogastric livestock production

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This review examines how Bacillus bacteria, when added to animal feed, can improve the health and growth of chickens and pigs. These bacteria work by producing beneficial compounds that strengthen the gut, improve digestion, reduce harmful bacteria, and boost the immune system. Bacillus probiotics offer a natural alternative to antibiotics, helping reduce antibiotic resistance while keeping animals healthier and more productive.

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Therapeutic Prospects of Undaria pinnatifida Polysaccharides: Extraction, Purification, and Functional Activity

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This review examines how to extract and purify beneficial compounds called polysaccharides from wakame seaweed (Undaria pinnatifida), a popular food in East Asia. These polysaccharides have multiple health benefits including fighting oxidative damage, boosting immune function, fighting cancer cells, and promoting healthy gut bacteria. The review details various extraction methods and discusses how these compounds could be developed into functional foods and medicines.

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Synergistic target network construction and dynamic simulation analysis based on a prospective systems pharmacology strategy

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Researchers used computer-based methods to study how Sang Huang, a traditional medicinal fungus, might help treat type 2 diabetes. They identified 17 active compounds in the fungus and found that a key component called estradiol dipropionate could improve insulin sensitivity and glucose control by activating specific protein pathways. The study suggests Sang Huang could be a promising natural treatment for diabetes, though more laboratory and animal testing is needed.

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Biochemical characteristics of extracts from proallergenic microfungi Erysiphe palczewskii and Erysiphe convolvuli

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Researchers studied two types of fungi that cause powdery mildew on plants and can trigger allergies in people who breathe in their spores. They discovered that these fungi contain proteins that act as allergens, including special proteins that help fungi survive stress. The fungi also contain high levels of linoleic acid, a fatty acid that can increase inflammation in the body. This research helps scientists understand why these fungi can cause allergic reactions and could help develop better diagnostic tools for fungal allergies.

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