Research Keyword: infectious disease

New approaches to tackle a rising problem: Large-scale methods to study antifungal resistance

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Fungal infections are becoming increasingly resistant to antifungal drugs, creating a serious public health challenge. Scientists are using advanced genetic sequencing and laboratory techniques to understand how fungi develop drug resistance and identify the specific genetic changes responsible. By cataloging resistance mutations and creating shared databases, researchers aim to develop better diagnostic tests and treatment strategies to combat these dangerous infections.

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Clinical, Laboratory, and Biomarker Predictors of 90-Day Mortality in Non-HIV, Non-Transplant Pneumocystis Pneumonia

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This study examined pneumocystis pneumonia in immunocompromised patients who do not have HIV or transplants. Researchers found that older patients with other health conditions were at higher risk of death within 90 days. High levels of fungal markers and low immune cell counts were better predictors of poor outcomes than traditional inflammation markers, suggesting doctors should focus on early identification and personalized treatment approaches.

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