Research Keyword: infection management

Evaluation of Clinical, Microbiological Profiles and Management Patterns with Outcomes of Patients with Fungal Isolates in An Intensive Care Unit of A Tertiary Care Center: A Prospective Observational Study

This study examined fungal infections in critically ill patients at a major hospital, tracking 120 patients and their fungal infections. Researchers found that diabetes was the most common risk factor, with most fungal infections occurring in urine samples and commonly caused by Candida tropicalis. The study revealed that many fungal strains were resistant to common antifungal drugs like fluconazole, suggesting that doctors need to carefully choose alternative treatments based on each patient’s specific infection type.

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Invasive Fungal Disease is Rare in Multiple Myeloma Patients Treated with BCMA CAR-T Therapy

Researchers studied 234 multiple myeloma patients who received a cutting-edge cancer treatment called BCMA CAR-T therapy. While this therapy can cause serious side effects related to immune system activation, the study found that dangerous fungal infections were surprisingly rare, occurring in only 1.7% of patients. However, when fungal infections did occur in these patients, they tended to be severe and life-threatening, highlighting the need for careful monitoring of high-risk patients.

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