Research Keyword: in vitro screening

In vitro compatibility screening of Bacillus pumilus and Bacillus altitudinis strains with selected candidate prebiotics for in ovo application of synergistic synbiotics

Researchers tested different beneficial bacteria (Bacillus strains) and food additives (prebiotics) to create improved formulations for chicken embryos. They found that certain plant-based additives, especially protein hydrolysate, worked particularly well with specific bacterial strains. When they tested the best combination in developing chicken eggs, it was completely safe and didn’t affect hatching rates, suggesting this approach could be used to give chicks a healthier start in life.

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Anticancer Activity of Solvent Extracts of Hexogonia glabra against Cervical Cancer Cell Lines

Researchers tested extracts from a wild mushroom species called Hexogonia glabra against cervical cancer cells in the laboratory. The ethanolic extract was most effective, killing cancer cells by triggering apoptosis (programmed cell death) and activating genes that fight cancer. The mushroom extracts showed strong anticancer effects without harming normal cells, suggesting it could be a promising source for developing new cancer drugs.

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Biological characterization and in vitro fungicide screening of a new causal agent of walnut leaf spot in Guizhou Province, China

Researchers in China discovered that a fungus called Didymella segeticola is causing a serious leaf spot disease in walnut trees in Guizhou Province. They studied how this fungus grows under different conditions and tested 20 different fungicides to find the most effective treatments. Two fungicides—difenoconazole and tetramycin—were found to be particularly effective at stopping the fungus, offering practical solutions for protecting walnut crops.

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Essential Oils as an Antifungal Alternative to Control Several Species of Fungi Isolated from Musa paradisiaca: Part II

Bananas often develop fungal infections during storage that reduce their quality. Researchers tested whether essential oils from common herbs and spices like cinnamon, clove, and oregano could prevent these fungal infections. The study found that cinnamon, clove, and oregano oils effectively stopped fungal growth at higher concentrations, offering a natural alternative to chemical fungicides that could help keep bananas fresh longer without synthetic chemicals.

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Biocontrol Potential of Bacillus velezensis RS65 Against Phytophthora infestans: A Sustainable Strategy for Managing Tomato Late Blight

Researchers tested 30 soil bacteria from tomato roots to find natural disease fighters. They discovered that Bacillus velezensis RS65, a beneficial bacterium, effectively prevents tomato late blight by producing enzymes and toxins that kill the fungal pathogen. In greenhouse tests, plants treated with RS65 had half the disease severity compared to untreated plants, suggesting this bacteria could replace chemical fungicides in sustainable tomato farming.

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