immunomodulation – Page 3

Tumor-associated macrophages in tumor progression and the role of traditional Chinese medicine in regulating TAMs to enhance antitumor effects

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This review explains how tumor-associated macrophages (immune cells) can either fight or help cancer depending on their type. Traditional Chinese Medicine contains compounds that can reprogram these macrophages to fight cancer more effectively. By shifting macrophages from a cancer-supporting state to a cancer-fighting state, TCM treatments could enhance the body’s natural ability to combat tumors and reduce side effects of conventional cancer therapies.

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo

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Researchers tested a mushroom extract from Cordyceps militaris to see if it could protect mice from lung injury caused by bacterial toxins. The extract successfully reduced inflammation, prevented excessive mucus production, and decreased immune cell buildup in the lungs. These findings suggest that this mushroom extract could potentially be used as a natural supplement to help prevent respiratory diseases and support lung health.

Bibliometric analysis of traditional Chinese medicine for viral infections through immune modulation (2015–2025)

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This research analyzed over 3,300 scientific papers published between 2015-2025 to understand how traditional Chinese medicine helps fight viral infections by boosting the immune system. The study found that research on this topic has grown significantly, especially during disease outbreaks like COVID-19, with China leading in research publications. Key findings show that traditional Chinese herbal compounds work through multiple mechanisms including directly fighting viruses, reducing excessive inflammation, and enhancing vaccine effectiveness. The research points toward promising future applications of traditional Chinese medicine when combined with modern medical approaches.

Proteins from Edible Mushrooms: Nutritional Role and Contribution to Well-Being

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Mushrooms are nutritional powerhouses containing as much high-quality protein as meat and soybeans, with complete amino acid profiles needed for human health. Beyond basic nutrition, mushroom proteins possess remarkable healing properties including anti-cancer, immune-boosting, and blood pressure-lowering effects. These sustainable proteins are increasingly used in food fortification, sports supplements, and therapeutic medicines. Growing mushrooms as mycelium or using novel cultivation methods makes protein production faster, more efficient, and environmentally friendly.

Koumiss (Fermented Mare’s Milk) as a Functional Food: Bioactive Proteins, Peptides, and Future Perspectives

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Koumiss is a fermented mare’s milk beverage consumed for centuries in Central Asia that offers unique health benefits. Unlike cow’s milk, mare’s milk is easier to digest, contains natural antimicrobial proteins, and when fermented develops thousands of bioactive peptides and beneficial bacteria. These compounds may help with cardiovascular health, gut function, and immune support, making koumiss a promising functional food for modern nutrition.

Nature’s Own Pharmacy: Mushroom-Based Chemical Scaffolds and Their Therapeutic Implications

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This comprehensive review explores how mushrooms can be used as natural medicines. Various mushroom species contain powerful compounds that can fight cancer, boost immunity, reduce inflammation, and treat infections. The paper details 15 important medicinal mushrooms and their therapeutic uses, showing that mushrooms are indeed a nature’s pharmacy with significant potential for treating many diseases.

Therapeutic Prospects of Undaria pinnatifida Polysaccharides: Extraction, Purification, and Functional Activity

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This review examines how to extract and purify beneficial compounds called polysaccharides from wakame seaweed (Undaria pinnatifida), a popular food in East Asia. These polysaccharides have multiple health benefits including fighting oxidative damage, boosting immune function, fighting cancer cells, and promoting healthy gut bacteria. The review details various extraction methods and discusses how these compounds could be developed into functional foods and medicines.

Anti-Inflammatory Effects of Solanum tuberosum L. Polysaccharide and Its Limited Gene Expression Profile

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Researchers studied a natural compound from potatoes called STP that reduces inflammation in the body. Using laboratory cells and animal models, they found that STP works similarly to the common pain reliever ibuprofen by reducing inflammatory chemicals and activating the body’s protective defense systems. This discovery suggests that potato-based polysaccharides could be developed into new treatments for inflammatory diseases and conditions related to oxidative stress.

Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

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Mushrooms are nutritional powerhouses packed with proteins, vitamins, minerals, and special compounds that fight disease. They can help prevent and manage serious conditions like cancer, heart disease, and diabetes while supporting overall health and immunity. Beyond the kitchen, mushrooms are being developed into medicines and cosmetic products. Growing and using mushrooms also helps the environment by creating sustainable alternatives to traditional medicines and animal feeds.

The Effect of Fungal Nutraceutical Supplementation on Postoperative Complications, Inflammatory Factors and Fecal Microbiota in Patients Undergoing Colorectal Cancer Surgery with Curative Intent: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial

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Researchers tested whether a supplement made from nine different medicinal mushroom types could reduce complications after colorectal cancer surgery. While the supplement didn’t significantly reduce overall complications, it did appear to boost immune function in patients undergoing traditional surgery and favorably changed the composition of gut bacteria. The supplement was well-tolerated with no serious side effects.

Research Keyword: immunomodulation