Research Keyword: immunomodulation

Multidisciplinary Integrative Medicine Approach for Cancer Patients: A Multicenter Retrospective Study

This study shows that when cancer patients use complementary treatments like mushroom supplements, vitamins, and probiotics alongside their cancer medications under doctor supervision, they experience fewer side effects and better quality of life. Almost 93% of patients had no side effects from these supplements, and many reported less fatigue and better overall wellness. The key finding is that patients should work with their medical team rather than self-prescribing these treatments to avoid dangerous interactions.

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Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials

This comprehensive review examines how medicinal mushrooms contain natural compounds that can boost immune function, fight cancer cells, reduce inflammation, and protect nerve cells. Different mushroom species like reishi, shiitake, and maitake contain various active substances such as beta-glucans and triterpenes that work through multiple biological pathways. While laboratory and animal studies show promising results, more human clinical trials are needed to confirm effectiveness and establish safe dosing guidelines.

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Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake

Researchers studied a combination of three medicinal mushroom extracts to see if they work better together than separately. They tested this formula on human immune cells called macrophages and found that the combination was significantly more powerful at boosting immune responses than any single mushroom extract alone. This synergistic effect means the three mushrooms enhance each other’s immune-stimulating properties, suggesting this formula combination could have potential therapeutic benefits for immune support.

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Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy

This review examines how traditional Chinese medicine ingredients can boost the body’s natural ability to fight cancer when combined with tiny nanoparticles that deliver drugs more effectively. The nanoparticles help TCM compounds work better by improving how they dissolve, how long they stay in the body, and where they target. By activating immune cells like natural killer cells and dendritic cells while reducing immune-suppressing cells, this combination approach offers a promising new strategy for cancer treatment with fewer side effects.

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A Review of the Role of Paraprobiotics in the Formulation of High-Protein Ice Cream as an Advanced Functional Food

Paraprobiotics are inactivated bacterial cells that offer the same health benefits as live probiotics but are much more stable and don’t require refrigeration. When added to high-protein ice cream, paraprobiotics help boost immune function and gut health while improving the product’s texture and shelf-life. This makes paraprobiotic-enriched ice cream an ideal functional dessert for athletes, people with dietary restrictions, and anyone seeking healthier frozen food options.

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Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes

Mushrooms are nutritious foods that contain beneficial compounds like β-glucans and polysaccharides which can help wounds heal faster. These compounds work by activating immune cells and promoting collagen production, which are essential for skin repair. Research shows that mushroom extracts from species like Ganoderma lucidum and Hericium erinaceus can accelerate wound closure in experimental models and may benefit diabetic wound care and burn treatment.

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Metabolite Profiles and Biological Activities of Different Phenotypes of Beech Mushrooms (Hypsizygus marmoreus)

This study compared white and brown varieties of beech mushrooms, which are popular edible mushrooms in South Korea. Brown beech mushrooms were found to have higher levels of beneficial compounds called phenolics, which give them a more bitter taste and brown color. The research showed that brown mushrooms have stronger health-promoting properties, including better abilities to fight bacteria, reduce inflammation, and combat oxidative stress, making them potentially more valuable as functional foods for health and nutrition.

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Medicinal Mushrooms as Multicomponent Mixtures—Demonstrated with the Example of Lentinula edodes

Shiitake mushrooms are more than just tasty food—they contain numerous compounds that work together to improve health. Unlike single isolated drugs, whole mushroom preparations offer multiple benefits including boosting immunity, protecting the heart, and potentially supporting cancer treatment. These mushrooms have been used safely in Asian medicine for over 2000 years and are becoming recognized worldwide for their health-promoting properties.

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Structural and Biological Properties of Rhamnogalacturonan-I-Enriched Pectin Isolated from Cardamine tangutorum and Cardamine macrophylla

Shigecai, a traditional vegetable eaten by Tibetan and Qiang communities, contains special fiber-like compounds called pectins that may be beneficial for health. Researchers found these compounds can help fight free radicals in the body, support healthy gut bacteria, and boost immune function. The study suggests these plants could be developed into health supplements and functional food ingredients.

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The Role of Wolfiporia cocos (F. A. Wolf) Ryvarden and Gilb. Polysaccharides in Regulating the Gut Microbiota and Its Health Benefits

Wolfiporia cocos, a fungus used in traditional Chinese medicine for over 2000 years, contains polysaccharides that act as prebiotics to improve gut health. These polysaccharides promote the growth of beneficial bacteria while inhibiting harmful ones, increase production of healthy metabolites, and strengthen the intestinal barrier. By improving gut microbiota composition, these polysaccharides can help prevent and treat various diseases including obesity, diabetes, and inflammatory conditions.

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