Immune response – mycolab.ai

Exploring the Therapeutic Potential of Ganoderma lucidum in Cancer

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Ganoderma lucidum, a mushroom used in traditional medicine for thousands of years, shows promise in fighting certain blood cancers like leukemia and lymphoma. The mushroom contains special compounds that can kill cancer cells in multiple ways—by triggering cancer cell death, boosting the immune system, and preventing cancer cell growth. While laboratory studies are very encouraging, more testing in humans is needed before it can be used as a standard cancer treatment.

Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials

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This comprehensive review examines how medicinal mushrooms contain natural compounds that can boost immune function, fight cancer cells, reduce inflammation, and protect nerve cells. Different mushroom species like reishi, shiitake, and maitake contain various active substances such as beta-glucans and triterpenes that work through multiple biological pathways. While laboratory and animal studies show promising results, more human clinical trials are needed to confirm effectiveness and establish safe dosing guidelines.

Transcriptome Analysis Reveals Mechanisms of Stripe Rust Response in Wheat Cultivar Anmai1350

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Researchers studied how a wheat variety called Anmai1350 defends itself against a fungal disease called stripe rust caused by Puccinia striiformis. By analyzing gene activity at different time points after infection, they discovered that the wheat plant’s immune system activates multiple defense strategies, including producing toxic molecules called reactive oxygen species and defensive compounds called phytoalexins that prevent the fungus from spreading. This research helps scientists understand how to breed wheat varieties that can naturally resist this damaging disease and maintain crop yields.

Use of Medicinal Mushrooms in Layer Ration

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This review discusses how medicinal mushrooms can be added to chicken feed to improve egg production and boost chicken health, offering a natural alternative to antibiotics. Several types of mushrooms like shiitake and oyster mushrooms have been shown to increase egg quality, strengthen immunity against diseases, and reduce cholesterol in eggs. These findings support the use of mushrooms as a sustainable solution for organic egg farming without compromising production or health.

Prebiotics and Probiotics Supplementation in Pigs as a Model for Human Gut Health and Disease

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Pigs are excellent models for studying human digestive health because their gut anatomy and function closely resemble humans. This review shows that prebiotics (special food compounds) and probiotics (beneficial bacteria) can improve gut health and strengthen the intestinal barrier in both healthy pigs and those with infections. These findings suggest that similar treatments might help prevent and treat digestive diseases in humans.

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo

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Researchers tested a mushroom extract from Cordyceps militaris to see if it could protect mice from lung injury caused by bacterial toxins. The extract successfully reduced inflammation, prevented excessive mucus production, and decreased immune cell buildup in the lungs. These findings suggest that this mushroom extract could potentially be used as a natural supplement to help prevent respiratory diseases and support lung health.

Tumor-associated macrophages in tumor progression and the role of traditional Chinese medicine in regulating TAMs to enhance antitumor effects

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This review explains how tumor-associated macrophages (immune cells) can either fight or help cancer depending on their type. Traditional Chinese Medicine contains compounds that can reprogram these macrophages to fight cancer more effectively. By shifting macrophages from a cancer-supporting state to a cancer-fighting state, TCM treatments could enhance the body’s natural ability to combat tumors and reduce side effects of conventional cancer therapies.

Effects of Ganoderma lucidum Powder on the Growth Performance, Immune Organ Weights, Cecal Microbiology, Serum Immunoglobulins, and Tibia Minerals of Broiler Chickens

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Researchers tested whether powdered Ganoderma lucidum mushroom could replace antibiotic growth promoters in chicken farming. The study found that adding 0.2% mushroom powder to chicken feed improved weight gain and feed efficiency similar to antibiotics, while also promoting beneficial gut bacteria. The mushroom powder was safe and did not cause any disease, making it a promising natural alternative to antibiotics in poultry production.

Immune regulatory functions of biologically active proteins from edible fungi

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This research compared how proteins from 22 different edible mushrooms affect immune system cells called macrophages. The study found that all the mushroom proteins tested boosted immune function by making macrophages more active and productive. Interestingly, expensive rare mushrooms like cordyceps and ganoderma lucidum had stronger immune-boosting effects than common grocery store mushrooms like oyster and button mushrooms.

Impacts of dietary sodium alginate as a prebiotic on the oriental river prawn (Macrobrachium nipponense): A comprehensive analysis of growth, physiology, immunity, antioxidant, and metabolism

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This study tested whether sodium alginate, a natural substance from brown seaweed, could improve the health and growth of freshwater prawns used in farming. After 60 days of feeding trials, prawns given the highest dose of sodium alginate (4.0 grams per kilogram of feed) showed significantly better growth, improved immune function, and stronger antioxidant defenses compared to control groups. The supplement also promoted beneficial bacteria in the prawns’ digestive systems and improved their overall body composition.

Research Keyword: Immune response