Research Keyword: IL-10

Anti-Inflammatory Effects of Solanum tuberosum L. Polysaccharide and Its Limited Gene Expression Profile

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Researchers studied a natural compound from potatoes called STP that reduces inflammation in the body. Using laboratory cells and animal models, they found that STP works similarly to the common pain reliever ibuprofen by reducing inflammatory chemicals and activating the body’s protective defense systems. This discovery suggests that potato-based polysaccharides could be developed into new treatments for inflammatory diseases and conditions related to oxidative stress.

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Divergent Immunomodulatory Roles of Fungal DNA in Shaping Treg and Inflammatory Responses

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Different types of fungal DNA trigger different immune responses in the body. DNA from the common yeast Candida albicans promotes immune tolerance and protects T cells, similar to beneficial bacterial DNA. In contrast, DNA from the pathogenic fungus Cryptococcus neoformans triggers strong inflammatory immune responses. This discovery reveals that fungal DNA itself, not just fungal cell wall components, plays an important role in determining whether fungi are treated as friendly commensals or dangerous pathogens by the immune system.

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