IC50 – mycolab.ai

Chaga mushroom triterpenoids as adjuncts to minimally invasive cancer therapies: A review

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Chaga mushroom, a fungus that grows on birch trees, contains special compounds called triterpenoids that can kill cancer cells in laboratory tests. Some of these compounds, particularly inotodiol and betulinic acid, show anti-cancer activity similar to or better than conventional chemotherapy drugs. While promising, researchers need to improve how these compounds are absorbed in the body and test them more thoroughly in animals and humans before they can be used clinically.

Inhibition of Fusarium oxysporum growth in banana by silver nanoparticles: In vitro and in vivo assays

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Bananas are threatened by a fungal disease called Fusarium wilt that damages crops worldwide. Scientists tested tiny silver particles called nanoparticles as a treatment for this disease on banana plants. The treatment successfully reduced disease by about 68% when applied to the roots, showing promise as an alternative to traditional fungicides for protecting banana crops.

Inhibition of Fusarium oxysporum growth in banana by silver nanoparticles: In vitro and in vivo assays

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Researchers tested silver nanoparticles as a potential cure for Fusarium wilt, a serious fungal disease that damages banana crops worldwide. Using laboratory tests and greenhouse experiments with banana plants, they found that silver nanoparticles effectively killed the fungus and reduced disease symptoms by about 68% when applied to plant roots. The study shows that this nanotechnology approach could offer a new way to protect banana plantations from this devastating disease.

Cadmium and Lead Tolerance of Filamentous Fungi Isolated from Contaminated Mining Soils

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Researchers found several types of fungi thriving in extremely contaminated mining soils in Mexico. These fungi can survive in environments with toxic levels of lead and cadmium that would kill most organisms. The most promising fungus, Paecilomyces lilacinus, can tolerate both metals and could potentially be used to clean up heavily polluted mining sites by binding and immobilizing these dangerous metals in the soil.

Cadmium and Lead Tolerance of Filamentous Fungi Isolated from Contaminated Mining Soils

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Researchers isolated six types of fungi from mining-contaminated soil in Mexico that can survive in extremely toxic environments with high levels of lead and cadmium. These fungi have developed special strategies to handle these dangerous metals, with one species, Paecilomyces lilacinus, showing exceptional ability to tolerate both metals simultaneously. These findings suggest these fungi could be used to clean up contaminated soils in mining regions, offering hope for environmental remediation efforts.

Physicochemical Characteristics of Chitosan Extracted from Pleurotus ostreatus and Its Anticancer Activity Against the MDA-MB-231 Breast Cancer Cell Line

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Researchers extracted a compound called chitosan from oyster mushrooms (Pleurotus ostreatus) and tested its ability to fight breast cancer cells. The chitosan successfully killed cancer cells by triggering apoptosis, a natural cell death process, while showing promise as a safer alternative to conventional chemotherapy. The study demonstrates that mushroom-derived compounds could have significant therapeutic potential for cancer treatment with fewer side effects than traditional drugs.

Anti-Influenza Activity of Medicinal Material Extracts from Qinghai–Tibet Plateau

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Researchers tested extracts from traditional Tibetan medicinal plants, mushrooms, and lichens to see if they could fight influenza virus. They found that seven out of nine extracts could reduce influenza virus infection in laboratory cells, with a mushroom extract called Armillaria luteo-virens showing particularly strong antiviral effects. These results suggest that traditional medicinal materials from the Qinghai–Tibetan plateau could be valuable sources for developing new flu treatments that might work better against drug-resistant flu strains.

Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

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Researchers compared two types of medicinal fungi (Phylloporia crataegi and Phylloporia fontanesiae) to understand why one is better at fighting cancer. They used advanced techniques to examine the fungi’s chemicals, genes, and proteins, discovering that P. crataegi contains special compounds like trans-cinnamic acid that help kill cancer cells. This study provides important information for developing new cancer treatments from these fungi.

Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

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Two species of medicinal fungi were studied to understand why one was better at fighting cancer cells. Researchers analyzed the chemicals, genes, and proteins in both fungi and found that Phylloporia crataegi had much higher levels of cancer-fighting compounds and activated special cellular defense pathways that harm cancer cells. This research shows that medicinal fungi could be promising sources for developing new cancer treatments.

Research Keyword: IC50