Research Keyword: hypersensitivity

Erythema Nodosum Associated with Kerion: A Case Series and Narrative Review of the Literature

This paper describes a rare condition where patients develop painful red bumps on the shins (erythema nodosum) as a reaction to a severe scalp fungal infection (kerion) caused by Trichophyton mentagrophytes. The authors reviewed 23 similar cases and found that this reaction usually happens during antifungal treatment and resolves within about a week. Treatment with antifungal medications like griseofulvin, sometimes combined with anti-inflammatory steroids, is effective, though scarring of the scalp may remain.

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Chronic Urticaria Suspected to be Caused by a 13.5 mg Levonorgestrel Intrauterine Device (Skyla®)

A woman developed a chronic hive-like rash that lasted for two years after having a hormone-releasing intrauterine device (Skyla®) implanted. Extensive medical testing ruled out common causes like vitamin D deficiency and allergies. When the device was removed, the rash gradually disappeared completely over two years. This case suggests that the progesterone released from the device may have triggered an allergic reaction in this particular patient.

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