Research Keyword: hyalohyphomycosis

Sarocladium implicatum: an unusual agent of opportunistic infection in a COVID-19 patient

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A patient hospitalized with severe COVID-19 developed an unusual infection caused by a mold called Sarocladium implicatum, which typically affects plants. Due to weakened immune system from his illness and medications, the fungus spread to his bloodstream and lungs, causing persistent fever and a cavity in his lung. After molecular testing identified the fungus, he was treated with an antifungal medication called voriconazole, which successfully cured the infection.

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Invasive Trichoderma longibrachiatum breakthrough infection in a hematology patient

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A 61-year-old woman with blood cancer developed a severe and unusual double fungal infection caused by two mold species while being treated for a known fungal infection. Despite receiving multiple antifungal medications, her condition worsened and she ultimately died from multiple organ failure. The case is important because it demonstrates how Trichoderma fungi are becoming dangerous pathogens in very sick, immunocompromised patients, and a new drug called olorofim showed promising activity against this infection in laboratory tests.

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Sarocladium implicatum: an unusual agent of opportunistic infection in a COVID-19 patient

mycolabadmin

A 64-year-old man hospitalized with COVID-19 developed a serious fungal infection from Sarocladium implicatum, an unusual fungus rarely found in humans. The infection appeared in his bloodstream and lungs while his immune system was severely weakened by the virus and medications. Doctors identified the fungus using genetic testing and successfully treated him with voriconazole antifungal medication. This case highlights how COVID-19 patients in intensive care are vulnerable to rare opportunistic infections that require specialized laboratory testing to identify and treat.

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