Research Keyword: HPLC-MS

Advanced fermentation techniques enhance dioxolanone type biopesticide production from Phyllosticta capitalensis

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Researchers discovered that special fermentation techniques can significantly boost the production of natural pesticides from a beneficial fungus called Phyllosticta capitalensis. By using materials like glass wool during fermentation, they increased the production of specific bioactive compounds. The resulting extracts showed excellent effectiveness against garden pests like aphids and harmful nematodes, offering a natural alternative to synthetic pesticides for sustainable agriculture.

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Influences of substrate and tissue type on erinacine production and biosynthetic gene expression in Hericium erinaceus

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This study examined how different growing conditions and tissue types affect erinacine production in lion’s mane mushrooms. Researchers found that mycelium (the fungal threads) produced far more erinacines than fruit bodies, and that the type of growth medium significantly influenced which erinacines were produced. Interestingly, changes in erinacine production weren’t always reflected in gene activity levels, suggesting other cellular mechanisms control these beneficial compounds.

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Screening of Basidiomycete Strains Capable of Synthesizing Antibacterial and Antifungal Metabolites

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Researchers tested 18 different types of wood-decay fungi (basidiomycetes) to see if they could produce natural antibiotics and antifungal compounds. They found that 16 of the 18 strains successfully produced antimicrobial substances. Five strains were particularly promising, showing strong activity against dangerous bacteria including antibiotic-resistant strains. The study identified specific chemical compounds from these fungi that could potentially be developed into new medicines.

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