Research Keyword: HPLC analysis

Extraction, physicochemical properties, and antioxidant activity of natural melanin from Auricularia heimuer fermentation

Researchers optimized a method to extract melanin, a natural black pigment, from fermented wood ear mushrooms (Auricularia heimuer). Using microwave-assisted extraction with specific pH conditions, they achieved a 0.4% yield of pure melanin. The extracted melanin showed strong antioxidant properties and could be used as a natural, safe colorant and antioxidant in food and pharmaceutical products.

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Synergistic impact of arbutin and kaempferol-7-O-α-l-rhamnopyranoside from Nephelium lappaceum L. on whitening efficacy and stability of cosmetic formulations

This research demonstrates that a natural compound from rambutan seeds works synergistically with arbutin to create more effective skin whitening products. The combination is 35 times more potent than arbutin alone at preventing melanin production in skin cells. The resulting cosmetic formulation maintains its effectiveness and stability for approximately 5.2 months, offering a safer natural alternative to conventional skin lightening agents that can cause irritation.

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Hass Avocado (Persea americana Mill) Peel Extract Reveals Antimicrobial and Antioxidant Properties against Verticillium theobromae, Colletotrichum musae, and Aspergillus niger Pathogens Affecting Musa acuminata Colla Species, in Ecuador

Researchers tested whether avocado peel waste could help protect banana crops from fungal diseases. They extracted beneficial compounds from avocado peels and tested them against three harmful fungi that affect bananas. The results showed the extract worked best against one type of fungus and had good antioxidant properties, suggesting avocado peel could be a natural and sustainable way to protect banana crops.

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Enhancement of Perylenequinonoid Compounds Production from Strain of Pseudoshiraia conidialis by UV-Induced Mutagenesis

Researchers used UV light to mutate fungal strains that naturally produce powerful medicinal compounds called perylenequinones. These compounds show promise for treating cancer and viral infections through photodynamic therapy. Through careful mutagenesis and screening, they developed a superior fungal strain that produces over 2100 mg/L of these valuable compounds, far exceeding previous methods. The breakthrough highlights that focusing on multiple beneficial compounds rather than just one can lead to better commercial applications.

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Antifungal potential of Rhinacanthus nasutus extracts against the pathogenic fungus Cryptococcus neoformans

Researchers studied snake jasmine (Rhinacanthus nasutus), a plant used in traditional Thai medicine, to see if it could fight fungal infections caused by Cryptococcus neoformans, a dangerous pathogen that kills many people worldwide. They found that extract from the plant’s roots effectively slowed fungal growth and weakened the pathogen’s defenses by reducing its ability to produce protective melanin and capsules. Importantly, when combined with amphotericin B, a common antifungal drug, the plant extract worked even better together, suggesting it could enhance existing treatments.

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Research Progress on Nutritional Components, Functional Active Components, and Pharmacological Properties of Floccularia luteovirens

Floccularia luteovirens is a special mushroom from the Qinghai-Tibet Plateau that has been used in traditional Tibetan medicine for centuries. It is extremely nutritious, containing as much protein as meat and numerous beneficial compounds. Scientific research shows it can help fight disease, boost immunity, and even preserve food naturally, making it promising for development as a health supplement and functional food.

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Astragalus Shiitake—A Novel Functional Food with High Polysaccharide Content and Anti-Proliferative Activity in a Colorectal Carcinoma Cell Line

Scientists developed a new type of Shiitake mushroom by growing it on a special substrate enriched with Astragalus root. This novel mushroom contains significantly more beneficial polysaccharides than regular Shiitake. When tested against colorectal cancer cells, extracts from this mushroom showed strong cancer-fighting properties, with the ultrasound extraction method being most effective. This research suggests Astragalus Shiitake could become a powerful functional food for cancer prevention and treatment.

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Evaluation of the Cytotoxicity and Antifungal Efficacy of Crocus sativus (saffron) Petals on Clinical Isolates of Candida albicans

Researchers tested saffron petals as a natural antifungal treatment against Candida albicans, a common fungal infection. While the saffron extract was less potent than the standard drug fluconazole, it showed promise as a safer alternative with minimal toxicity to human cells. The findings suggest saffron petals could be a cost-effective herbal option for treating fungal infections, especially as resistance to conventional antifungals increases.

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Identification of the High Mannose N-Glycan Isomers Undescribed by Conventional Multicellular Eukaryotic Biosynthetic Pathways

Researchers developed a new method to identify the sugar structures attached to proteins in various foods and organisms. They discovered that many of these sugar structures are different from what scientists previously thought based on standard biological pathways. Using advanced mass spectrometry technology, they created a database to quickly identify these novel sugar structures, which could help better understand how organisms modify their proteins.

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Molecular identification and mycotoxins analysis of some fungal isolates from postharvest decayed apple in Qena, Egypt

Apples stored after harvest can be infected by blue mold fungi that produce toxic substances called mycotoxins. Researchers in Egypt identified five fungal strains from rotted apples and measured the amounts of two dangerous toxins they produce. The findings show that these fungi can cause significant food safety risks and economic losses, highlighting the need for better storage and handling practices.

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