Research Keyword: HPLC analysis

Isolation and Evaluation of Erinacine A Contents in Mycelia of Hericium erinaceus Strains

Researchers developed a new method to extract and purify erinacine A, a beneficial compound from lion’s mane mushrooms, using an advanced separation technique called high-speed countercurrent chromatography. They tested 15 different mushroom strains and found that a wild strain called HeG produced significantly more erinacine A than commercially cultivated varieties. Erinacine A shows promise for protecting brain health and potentially helping with diseases like Alzheimer’s and Parkinson’s. This discovery could help make erinacine A supplements more accessible and affordable for consumers.

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Exploring the Nutritional Value and Bioactive Potential of Craterellus cornucopioides (L.) Pers. as a Functional Food Source

Black trumpet mushrooms from Romania have been found to contain high levels of beneficial compounds that protect cells from damage and fight harmful bacteria. The mushrooms showed strong antioxidant properties in laboratory tests and were effective against several disease-causing bacteria, though not against all types tested. These results suggest that black trumpets could be used as a natural supplement or food ingredient to support health and potentially help treat infections.

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A putative ABC transporter gene, CcT1, is involved in beauvericin synthesis, conidiation, and oxidative stress resistance in Cordyceps chanhua

Cordyceps chanhua is a medicinal fungus used in traditional Chinese medicine that produces a compound called beauvericin, which has health benefits but can be toxic in high amounts. Researchers discovered a gene called CcT1 that controls how much beauvericin the fungus makes. By removing this gene, they could reduce beauvericin production by 64%, making the fungus safer to use as medicine while maintaining other beneficial properties.

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Clinical Implementation of Sustainable Functional Foods and Nutraceuticals in Metabolic Health: A Feasibility Study

Researchers tested a combination of special foods and supplements made from Mediterranean plants like tomatoes, pomegranates, and hazelnuts to see if they could help people with metabolic health problems. Over 4 weeks, older adults who consumed these foods daily showed improvements in muscle, bone quality, and liver health. The products tasted good and people stuck with them easily, suggesting this approach could be a practical way to improve health through diet.

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Production of Myco-Nanomaterial Products from Pleurotus ostreatus (Agaricomycetes) Mushroom via Pyrolysis

Scientists have discovered a new way to create tiny fluorescent particles called carbon nanodots from oyster mushrooms using heat treatment. These particles glow under certain light conditions and show promising ability to fight bacteria like E. coli. The process is environmentally friendly, uses waste mushroom material, and could lead to new ways to treat infections and reduce dependence on antibiotics.

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Impact of a Limosilactobacillus fermentum, Quercetin, and Resveratrol Nutraceutical on Fecal Microbiota Composition and Metabolic Activity in Healthy and Hypertensive Subjects

Researchers tested a dietary supplement containing beneficial bacteria and plant compounds on human gut microbiota samples. The supplement successfully modified the composition and activity of gut bacteria in both healthy and high blood pressure patients. The supplement increased production of beneficial acids and modified which bacteria were present in the fermentation samples. These findings suggest this type of supplement could potentially help manage high blood pressure by improving gut health.

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Amelioration of Ulcerative Colitis in BALB/c Mice by Probiotic-Fermented Aegle marmelos Juice

Researchers tested a fermented bael fruit juice with probiotics as a treatment for ulcerative colitis in mice. The mice treated with this juice showed significant improvement in weight recovery, reduced inflammation markers, and increased antioxidant protection compared to untreated diseased mice. The fermentation process increased the beneficial compounds in the juice. These results suggest that probiotic-fermented bael fruit juice could be a natural and effective treatment option for people with ulcerative colitis.

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Patulin Biodegradation by Rhodosporidiobolus ruineniae and Meyerozyma guilliermondii Isolated From Fruits

Patulin is a dangerous toxin produced by molds that grow on apples and peaches, posing serious health risks to consumers. Researchers isolated two yeast species from fruits that can effectively break down patulin into a less toxic compound called (E)-ascladiol. The yeasts work by using enzymes inside their cells to degrade the toxin, and this biological approach could be used to safely remove patulin from contaminated fruits and fruit products.

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Phytochemical Analysis and Anti-Ulcer Potential of Phenolic Compounds of Inonotus nidus-pici Pilát

Researchers studied a wood mushroom called Inonotus nidus-pici to understand its healing potential. They found it contains beneficial compounds like quercetin and rosmarinic acid that act as antioxidants. When tested on rats with chemically-induced stomach ulcers, the mushroom extract provided protection similar to common ulcer medications, suggesting it could help prevent stomach damage from pain relievers.

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Clinical Isolate of Candida tropicalis from a Patient in North Carolina: Identification, Whole-Genome Sequence Analysis, and Anticandidal Activity of Ganoderma lucidum

Researchers in North Carolina identified a drug-resistant yeast infection (Candida tropicalis) from a hospital patient and tested whether extracts from reishi mushrooms (Ganoderma lucidum) could kill it. Using genetic analysis, they found mutations in the yeast that help it resist antifungal drugs. All three types of mushroom extracts tested successfully stopped the yeast’s growth and damaged its cells, suggesting that reishi mushrooms could be a promising natural treatment option for hard-to-treat candida infections.

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